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Previous Issue Next Issue

American Journal of Psychiatry

Volume 155, Issue 12

December 1998

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Editorial

December 1998

Understanding Schizophrenia: A Silent Spring?

N.C.A.

Pages:1657–1659
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1657

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Images In Neuroscience

December 1998

Brain Development, VIII: The Reeler Mouse

PAUL J. LOMBROSO, M.D., New Haven, Conn., and
DANIEL GOLDOWITZ, PH.D., Memphis, Tenn.

Page:1660
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1660

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Special Article

December 1998

Is Schizophrenia a Progressive Neurodevelopmental Disorder? Toward a Unitary Pathogenetic Mechanism

Bryan T. Woods, M.D.

Pages:1661–1670
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1661

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Objective:The author 1) reassesses the case against a neuronal degeneration hypothesis for schizophrenia; 2) demonstrates that the hypothesis that schizophrenia is a disorder caused by early (i.e., pre- or perinatal) and static (i.e., fixed, ...

Regular Article

December 1998

Cognitive Substrates of Thought Disorder, I: The Semantic System

Terry E. Goldberg, Ph.D.,
Mark S. Aloia, Ph.D.,
Monica L. Gourovitch, Ph.D.,
David Missar, Ph.D.,
David Pickar, M.D., and
Daniel R. Weinberger, M.D.

Pages:1671–1676
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1671

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Objective:Few studies have explored in detail the relation of cognitive deficits in attention, working memory, and semantics to thought disorder. The authors sought to determine whether thought disorder resides in the semantic system or elsewhere. Method:...

December 1998

Cognitive Substrates of Thought Disorder, II: Specifying a Candidate Cognitive Mechanism

Mark S. Aloia, Ph.D.,
Monica L. Gourovitch, Ph.D.,
David Missar, Ph.D.,
David Pickar, M.D.,
Daniel R. Weinberger, M.D., and
Terry E. Goldberg, Ph.D.

Pages:1677–1684
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1677

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Objective:In part I of this series, the authors found that semantic knowledge and organization accounted for most of the variance in thought disorder in a group of chronic schizophrenic patients. In the present study, they examined a possible cognitive ...

December 1998

Word Recall in Schizophrenia: A Connectionist Model

Paul G. Nestor, Ph.D.,
Sare J. Akdag, B.S.,
Brian F. O’Donnell, Ph.D.,
Margaret Niznikiewicz, Ph.D.,
Sue Law, M.A.,
Martha E. Shenton, Ph.D., and
Robert W. McCarley, M.D.

Pages:1685–1690
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1685

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Objective:The authors examined word recall of patients with schizophrenia by using an experimental paradigm generated from connectionist models of memory.Method:Schizophrenic patients and normal comparison subjects first studied and then recalled a list ...

December 1998

Poor P50 Suppression Among Schizophrenia Patients and Their First-Degree Biological Relatives

Brett A. Clementz, Ph.D.,
Mark A. Geyer, Ph.D., and
David L. Braff, M.D.

Pages:1691–1694
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1691

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Objective:This study’s goal was to replicate the finding that family members of schizophrenia patients show poor P50 suppression during a paired-click auditory evoked response paradigm. Method:The paired-click paradigm was used to test 44 schizophrenia ...

December 1998

Minor Physical Anomalies in Schizophrenic Patients and Their Siblings

Baher Ismail, M.D.,
Elizabeth Cantor-Graae, Ph.D., and
Thomas F. McNeil, Ph.D.

Pages:1695–1702
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1695

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Objective:The aim of this study was to assess the frequency and type of minor physical anomalies in schizophrenic patients and their normal siblings.Method:Sixty adult patients with schizophrenia, 21 siblings of these patients, and 75 normal comparison ...

December 1998

Saccadic Eye Movements in Families Multiply Affected With Schizophrenia: The Maudsley Family Study

T.J. Crawford, Ph.D.,
T. Sharma, M.R.C.Psych.,
B.K. Puri, M.R.C.Psych.,
R.M. Murray, M.D.,
D.M. Berridge, Ph.D., and
S.W. Lewis, M.D.

Pages:1703–1710
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1703

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Objective:Family studies have shown that abnormalities of smooth pursuit eye movement are increased in the adult relatives of schizophrenic probands as well as in the probands themselves. More recently, an inability of schizophrenic subjects to inhibit ...

December 1998

Subcortical MRI Volumes in Neuroleptic-Naive and Treated Patients With Schizophrenia

Raquel E. Gur, M.D., Ph.D.,
Veda Maany, B.A.,
P. David Mozley, M.D.,
Charlie Swanson, M.D.,
Warren Bilker, Ph.D., and
Ruben C. Gur, Ph.D.

Pages:1711–1717
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1711

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Objective:This study examined whether subcortical volumes of the basal ganglia and thalamus in schizophrenic patients are related to neuroleptic exposure and symptom severity. Method:Basal ganglia substructures and thalamic volumes were measured with ...

December 1998

Stress Reactions of Children and Adolescents in War and Siege Conditions

Syed Arshad Husain, M.D.,
Jyotsna Nair, M.D.,
William Holcomb, Ph.D.,
John C. Reid, Ph.D.,
Victor Vargas, M.S., and
Satish S. Nair, Ph.D.

Pages:1718–1719
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1718

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Objective:This was a study of posttraumatic stress symptoms in children and adolescents during siege conditions in Sarajevo.Method:Seven hundred ninety-one students aged 7–15 years were surveyed to assess symptoms of posttraumatic stress and level of ...

December 1998

Testimony Psychotherapy in Bosnian Refugees: A Pilot Study

Stevan M. Weine, M.D.,
Alma Dzubur Kulenovic, M.D.,
Ivan Pavkovic, M.D., and
Robert Gibbons, Ph.D.

Pages:1720–1726
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1720

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Objective:The authors sought to describe the use of the testimony method of psychotherapy in a group of traumatized adult refugees from genocide in Bosnia-Herzegovina. Method:The subjects were 20 Bosnian refugees in Chicago who gave written informed ...

December 1998

Prevalence of Symptoms of Posttraumatic Stress Disorder in German Professional Firefighters

Dieter Wagner, M.S.,
Markus Heinrichs, M.S., and
Ulrike Ehlert, Ph.D.

Pages:1727–1732
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1727

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Objective:This study investigated the prevalence of posttraumatic stress disorder (PTSD) and comorbid symptoms among professional firefighters in Germany and examined not only primary but also secondary traumatic stress disorder experienced by these ...

December 1998

Axis I Comorbidity of Borderline Personality Disorder

Mary C. Zanarini, Ed.D.,
Frances R. Frankenburg, M.D.,
Elyse D. Dubo, M.D.,
Amy E. Sickel, M.A.,
Anjana Trikha, Ph.D.,
Alexandra Levin, A.B., and
Victoria Reynolds, M.A.

Pages:1733–1739
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1733

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Objective:The purpose of this study was to assess the lifetime rates of occurrence of a full range of DSM-III-R axis I disorders in a group of patients with criteria-defined borderline personality disorder and comparison subjects with other personality ...

December 1998

Comorbidity and Course of Psychiatric Disorders in a Community Sample of Former Prisoners of War

Brian Engdahl, Ph.D.,
Thomas N. Dikel, M.A.,
Raina Eberly, Ph.D., and
Arthur Blank, M.D.

Pages:1740–1745
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1740

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Objective:The authors assessed DSM-III-R disorders among American former prisoners of war. Comorbidity, time of onset, and the relationship of trauma severity to complicated versus uncomplicated posttraumatic stress disorder (PTSD) were examined. Method:A ...

December 1998

Major Depression in Individuals With a History of Childhood Physical or Sexual Abuse: Relationship to Neurovegetative Features, Mania, and Gender

Robert D. Levitan, M.D.,
Sagar V. Parikh, M.D.,
Alain D. Lesage, M.D.,
Kathleen M. Hegadoren, Ph.D.,
Martha Adams, M.D.,
Sidney H. Kennedy, M.D., and
Paula N. Goering, Ph.D.

Pages:1746–1752
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1746

Abstract
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Objective:Numerous studies have linked childhood trauma with depressive symptoms over the life span. However, it is not known whether particular neurovegetative symptom clusters or affective disorders are more closely linked with early abuse than are ...

December 1998

Association of Recurrent Suicidal Ideation With Nonremission From Acute Mixed Mania

Joseph F. Goldberg, M.D.,
Jessica L. Garno, M.A.,
Andrew C. Leon, Ph.D.,
James H. Kocsis, M.D., and
Laura Portera, M.S.

Pages:1753–1755
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1753

Abstract
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Objective:The authors’ goal was to examine suicidality in relation to acute symptom remission in inpatients with mixed and pure bipolar disorder.Method:Using chart review of 184 adult inpatients with bipolar I disorder, the authors assessed patients’ past ...

December 1998

Fluvoxamine in the Treatment of Binge-Eating Disorder: A Multicenter Placebo-Controlled, Double-Blind Trial

James I. Hudson, M.D.,
Susan L. McElroy, M.D.,
Nancy C. Raymond, M.D.,
Scott Crow, M.D.,
Paul E. Keck, M.D.,
William P. Carter, M.D.,
James E. Mitchell, M.D.,
Stephen M. Strakowski, M.D.,
Harrison G. Pope, M.D.,
Bernard S. Coleman, M.D., and
Jeffrey M. Jonas, M.D.

Pages:1756–1762
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1756

Abstract
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Objective:The purpose of this study was to assess the efficacy of fluvoxamine in the treatment of binge-eating disorder. Binge-eating disorder is a newly described eating disorder characterized by recurrent episodes of binge eating but without purging ...

Clinical Case Conference

December 1998

The Role of Culture in Psychiatric Care

Pedro Ruiz, M.D.

Pages:1763–1765
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1763

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Images In Psychiatry

December 1998

Marie Nyswander, 1919–1986

THOMAS R. KOSTEN, M.D.

Page:1766
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1766

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Brief Report

December 1998

Limitations of Axis II in Diagnosing Personality Pathology in Clinical Practice

Drew Westen, Ph.D., and
Laura Arkowitz-Westen, Ph.D.

Pages:1767–1771
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1767

Abstract
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Objective:DSM-IV’s axis II is limited to severe personality disturbances, posing difficulty for diagnosing less severe but nonetheless clinically significant personality pathology. The authors examined the percentage of patients treated in clinical ...

December 1998

Private Psychotherapy Patients of Psychiatrist Psychoanalysts

Richard C. Friedman, M.D.,
Wilma Bucci, Ph.D.,
Christopher Christian, Ph.D.,
Philip Drucker, Ph.D., and
Webb Black Garrison, M.A.

Pages:1772–1774
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1772

Abstract
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Objective:The characteristics of private psychotherapy patients of medical psychoanalysts are described. Method:A structured interview was administered to 51 medical psychoanalysts. Patients’ demographic characteristics, historical features, and other ...

December 1998

Mental Disorders and Access to Medical Care in the United States

Benjamin G. Druss, M.D., M.P.H., and
Robert A. Rosenheck, M.D.

Pages:1775–1777
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1775

Abstract
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Objective:The authors examined the barriers to receipt of medical services among people reporting mental disorders in a representative sample of U.S. adults.Method:The sample was drawn from adults who responded to the 1994 National Health Interview Survey ...

December 1998

Inadequate Treatment for Major Depression Both Before and After Attempted Suicide

Kirsi H. Suominen, M.D.,
Erkki T. Isometsä, M.D., Ph.D.,
Markus M. Henriksson, M.D., Ph.D.,
Aini I. Ostamo, M.A., Lic.Soc.Sc., and
Jouko K. Lönnqvist, M.D., Ph.D.

Pages:1778–1780
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1778

Abstract
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Objective:The authors’ goal was to investigate the treatment received by suicide attempters with major depression before and after the index attempt.Method:Forty-three patients with current unipolar DSM-III-R major depression were identified in a ...

December 1998

Short-Term Single-Blind Fluvoxamine Treatment of Pathological Gambling

Eric Hollander, M.D.,
Concetta M. DeCaria, Ph.D.,
Eduardo Mari, B.A.,
Cheryl M. Wong, M.D.,
Serge Mosovich, M.D.,
Robert Grossman, M.D., and
Tomer Begaz, B.A.

Pages:1781–1783
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1781

Abstract
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Objective:The authors’ goal was to assess the efficacy and tolerability of the selective serotonin reuptake inhibitor fluvoxamine in the treatment of pathological gambling. Method:Sixteen patients with pathological gambling entered an 8-week placebo lead-...

December 1998

Partial Volume Decrease of the Thalamus in Relatives of Patients With Schizophrenia

Wouter G. Staal, M.D.,
Hilleke E. Hulshoff Pol, Ph.D.,
Hugo Schnack, Ph.D.,
Astrid C. van der Schot, M.S., and
René S. Kahn, M.D., Ph.D.

Pages:1784–1786
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1784

Abstract
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Objective:The authors’ goal was to compare the thalamic, total brain, and intracranial volumes of patients with schizophrenia, their healthy siblings, and normal comparison subjects.Method:Magnetic resonance imaging (MRI) brain scans were obtained for 32 ...

Book Forum: BIOGRAPHY

December 1998

Fermat’s Enigma: The Quest to Solve the World’s Greatest Mathematical Problem

DAVID V. FORREST, M.D., New York, N.Y.

Page:1787
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1787

First Page
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December 1998

Adolf Wölfli: Draftsman, Writer, Poet, Composer

JOSEPH J. SCHILDKRAUT, M.D., Boston, Mass.

Pages:1787a–1788
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1787a

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December 1998

Explaining Hitler: The Search for the Origins of His Evil

WILLIAM EDWIN FANN, M.D., Houston, Tex.

Pages:1788–1789
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1788

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December 1998

The Two Mr. Gladstones: A Study in Psychology and History

ANTHONY W. CLARE, M.D., F.R.C.PSYCH., F.R.C.P., Dublin, Ireland

Pages:1789–1790
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1789

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December 1998

The Sword of Laban: Joseph Smith, Jr., and the Dissociated Mind

DAN G. BLAZER, M.D., PH.D., Durham, N.C.

Page:1790
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1790

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Book Forum: LITERATURE

December 1998

Cities of the Plain

WILLIAM G. RYAN, M.D., Birmingham, Ala.

Page:1791
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1791

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December 1998

GLEN O. GABBARD, M.D., Topeka, Kan.

Pages:1791a–1792
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1791a

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December 1998

Homer: The Odyssey

RICHARD D. CHESSICK, M.D., PH.D., Evanston, Ill.

Pages:1792–1793
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1792

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December 1998

Writings on Art and Literature

RICHARD D. CHESSICK, M.D., PH.D., Evanston, Ill.

Pages:1793–1794
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1793

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Book Forum: HISTORY

December 1998

The History of Mental Symptoms: Descriptive Psychopathology Since the Nineteenth Century

PETER D. KRAMER, M.D., Providence, R.I.

Pages:1794–1795
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1794

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December 1998

The Greatest Benefit to Mankind: A Medical History of Humanity

DONALD W. GOODWIN, M.D., Kansas City, Kan.

Pages:1795–1796
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1795

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December 1998

Consilience: The Unity of Knowledge

DAVID V. FORREST, M.D., New York, N.Y.

Pages:1796–1797
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1796

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December 1998

The Prehistory of the Mind: The Cognitive Origins of Art, Religion and Science

ROBERT CANCRO, M.D., New York, N.Y.

Page:1797
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1797

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Letter to the Editor

December 1998

Comments on the APA Panic Disorder Guideline

Robert T. Fintzy, M.D., Los Angeles, Calif.

Page:1798
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1798

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December 1998

Comments on the APA Panic Disorder Guideline

Anton J.L.M. van Balkom, M.D., Ph.D., and
Richard van Dyck, M.D., Ph.D., Amsterdam, The Netherlands

Pages:1798a–1798
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1798a

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December 1998

Comments on the APA Panic Disorder Guideline

Robert L. Pyles, M.D., President, Wellesley Hills, Mass.,
Richard P. Fox, M.D., President-Elect, and
Donald Rosenblitt, M.D., Chair, Board on Professional Standards

Pages:1798b–1798
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1798b

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December 1998

Comments on the APA Panic Disorder Guideline

Fredric N. Busch, M.D., New York, N.Y.,
Barbara L. Milrod, M.D., and
Glen O. Gabbard, M.D.

Pages:1798c–1799
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1798c

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December 1998

Drs. Gorman, Shear, McIntyre, and Zarin Reply

Jack M. Gorman, M.D., Co-chair, Panic Disorder Practice Guideline Work Group,
M. Katherine Shear, M.D., Co-chair, Panic Disorder Practice Guideline Work Group,
John S. McIntyre, M.D., Chair, Steering Committee on Practice Guidelines, and
Deborah A. Zarin, M.D., Deputy Medical Director, Washington, D.C.

Pages:1799–1800
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1799

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Correction

December 1998

Page:1800
Published Online:1 December 1998

https://doi.org/10.1176/ajp.155.12.1800

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