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American Journal of Psychiatry

Volume 178, Issue 9

September 2021

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Editor’s Note

September 2021

Insights Into Improving Clinical Outcomes Across Psychiatric Disorders and Medical Comorbidities

Ned H. Kalin, M.D.

Pages:779–782
Published Online:13 September 2021

https://doi.org/10.1176/appi.ajp.2021.21070710

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Editorials

September 2021

Cigarette Smoking and Heavy Alcohol Drinking: The Challenges and Opportunities for Combination Treatments

Andrea King, Ph.D.,
Lisa Fucito, Ph.D.

Pages:783–785
Published Online:13 September 2021

https://doi.org/10.1176/appi.ajp.2021.21070692

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September 2021

From Awareness to Action: An Urgent Call to Address the Inadequacy of Treatment for Anorexia Nervosa

Cynthia M. Bulik, Ph.D.

Pages:786–788
Published Online:13 September 2021

https://doi.org/10.1176/appi.ajp.2021.21070697

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September 2021

The Conundrum of Treatment Discontinuation of Stimulant Medication for ADHD Despite Its Efficacy

Jonna Kuntsi, Ph.D.

Pages:789–790
Published Online:13 September 2021

https://doi.org/10.1176/appi.ajp.2021.21070689

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Commentary

September 2021

Behavior as Physiology: How Dynamical-Systems Theory Could Advance Psychiatry

Joshua D. Salvi, M.D., Ph.D.,
Scott L. Rauch, M.D.,
Justin T. Baker, M.D., Ph.D.

Pages:791–792
Published Online:13 September 2021

https://doi.org/10.1176/appi.ajp.2020.20081151

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Reviews and Overviews

September 2021

Disparities in Screening and Treatment of Cardiovascular Diseases in Patients With Mental Disorders Across the World: Systematic Review and Meta-Analysis of 47 Observational Studies

Marco Solmi, M.D., Ph.D.,
Jess Fiedorowicz, M.D., Ph.D.,
Laura Poddighe, M.Psy.,
Marco Delogu, M.Psy.,
Alessandro Miola, M.D.,
Anne Høye, M.D., Ph.D.,
Ina H. Heiberg, M.Sc., Ph.D.,
Brendon Stubbs, M.Sc., Ph.D.,
Lee Smith, M.Sc., Ph.D.,
Henrik Larsson, Ph.D.,
Rubina Attar, M.D.,
René E. Nielsen, M.D., Ph.D.,
Samuele Cortese, M.D., Ph.D.,
Jae Il Shin, M.D., Ph.D.,
Paolo Fusar-Poli, M.D.,
Joseph Firth, Ph.D.,
Lakshmi N. Yatham, M.B.B.S., F.R.C.P.C.,
Andre F. Carvalho, M.D., Ph.D.,
David J. Castle, M.D., F.R.C.Psych.,
Mary V. Seeman, M.D.,
Christoph U. Correll, M.D.

Pages:793–803
Published Online:14 July 2021

https://doi.org/10.1176/appi.ajp.2021.21010031

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Objective:This study used meta-analysis to assess disparities in cardiovascular disease (CVD) screening and treatment in people with mental disorders, a group that has elevated CVD incidence and mortality.Methods:The authors searched PubMed and PsycInfo ...

Articles

September 2021

Office-Based Methadone Treatment for Opioid Use Disorder and Pharmacy Dispensing: A Scoping Review

Dennis McCarty, Ph.D.,
Christina Bougatsos, M.P.H.,
Brian Chan, M.D., M.P.H.,
Kim A. Hoffman, Ph.D.,
Kelsey C. Priest, M.D., Ph.D.,
Sara Grusing, B.A.,
Roger Chou, M.D.

Pages:804–817
Published Online:28 July 2021

https://doi.org/10.1176/appi.ajp.2021.20101548

Abstract
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Objective:The authors conducted a scoping review to survey the evidence landscape for studies that assessed outcomes of treating patients with opioid use disorder with methadone in office-based settings.Methods:Ovid MEDLINE and the Cochrane Database of ...

September 2021

Efficacy of Combining Varenicline and Naltrexone for Smoking Cessation and Drinking Reduction: A Randomized Clinical Trial

Lara A. Ray, Ph.D.,
ReJoyce Green, M.A.,
Craig Enders, Ph.D.,
Adam M. Leventhal, Ph.D.,
Erica N. Grodin, Ph.D.,
Gang Li, Ph.D.,
Aaron Lim, M.A.,
Emily Hartwell, Ph.D.,
Alex Venegas, M.A.,
Lindsay Meredith, M.A.,
Steven J. Nieto, Ph.D.,
Steven Shoptaw, Ph.D.,
Diana Ho,
Karen Miotto, M.D.

Pages:818–828
Published Online:3 June 2021

https://doi.org/10.1176/appi.ajp.2020.20070993

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Objective:Pharmacological treatments that can concomitantly address cigarette smoking and heavy drinking stand to improve health care delivery for these highly prevalent co-occurring conditions. This superiority trial compared the combination of ...

September 2021

Effects of Gabapentin on Dorsal Anterior Cingulate Cortex GABA and Glutamate Levels and Their Associations With Abstinence in Alcohol Use Disorder: A Randomized Clinical Trial

James J. Prisciandaro, Ph.D.,
Michaela Hoffman, Ph.D.,
Truman R. Brown, Ph.D.,
Konstantin Voronin, M.D.,
Sarah Book, M.D.,
Emily Bristol, B.A.,
Raymond F. Anton, M.D.

Pages:829–837
Published Online:14 July 2021

https://doi.org/10.1176/appi.ajp.2021.20121757

Abstract
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Objective:Although gabapentin has demonstrated efficacy in mitigating alcohol withdrawal symptoms and preventing relapse drinking in individuals with alcohol use disorder (AUD), the neurobiological mechanisms of action underlying these therapeutic effects ...

September 2021

Anticholinergic Medication Burden–Associated Cognitive Impairment in Schizophrenia

Yash B. Joshi, M.D., Ph.D.,
Michael L. Thomas, Ph.D.,
David L. Braff, M.D.,
Michael F. Green, Ph.D.,
Ruben C. Gur, Ph.D.,
Raquel E. Gur, M.D., Ph.D.,
Keith H. Nuechterlein, Ph.D.,
William S. Stone, Ph.D.,
Tiffany A. Greenwood, Ph.D.,
Laura C. Lazzeroni, Ph.D.,
Laura R. MacDonald, B.S.,
Juan L. Molina, M.D.,
John A. Nungaray, B.S.,
Allen D. Radant, M.D.,
Jeremy M. Silverman, Ph.D.,
Joyce Sprock, B.A.,
Catherine A. Sugar, Ph.D.,
Debby W. Tsuang, M.D., Ph.D.,
Ming T. Tsuang, M.D., Ph.D.,
Bruce I. Turetsky, M.D.,
Neal R. Swerdlow, M.D., Ph.D.,
Gregory A. Light, Ph.D.

Pages:838–847
Published Online:14 May 2021

https://doi.org/10.1176/appi.ajp.2020.20081212

Abstract
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Objective:Many psychotropic medications used to treat schizophrenia have significant anticholinergic properties, which are linked to cognitive impairment and dementia risk in healthy subjects. Clarifying the impact of cognitive impairment attributable to ...

September 2021

Time Course of Relapse Following Acute Treatment for Anorexia Nervosa

B. Timothy Walsh, M.D.,
Tianchen Xu, M.S.,
Yuanjia Wang, Ph.D.,
Evelyn Attia, M.D.,
Allan S. Kaplan, M.D.

Pages:848–853
Published Online:22 June 2021

https://doi.org/10.1176/appi.ajp.2021.21010026

Abstract
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Objective:There is long-standing interest in how best to define stages of illness for anorexia nervosa, including remission and recovery. The authors used data from a previously published study to examine the time course of relapse over the year following ...

September 2021

Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD

Isabell Brikell, Ph.D.,
Theresa Wimberley, Ph.D.,
Clara Albiñana, M.Sc.,
Emil Michael Pedersen, M.Sc.,
Bjarni Jóhann Vilhjálmsson, Ph.D.,
Esben Agerbo, Ph.D.,
Ditte Demontis, Ph.D.,
Anders D. Børglum, Ph.D.,
Andrew J. Schork, Ph.D.,
Sonja LaBianca, Ph.D.,
Thomas Werge, Ph.D.,
Ole Mors, Ph.D., M.D.,
David M. Hougaard, Ph.D.,
Anita Thapar, Ph.D.,
Preben Bo Mortensen, Ph.D.,
Søren Dalsgaard, Ph.D.

Pages:854–864
Published Online:22 June 2021

https://doi.org/10.1176/appi.ajp.2020.20121686

Abstract
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Objective:Stimulant medications are effective for treating attention deficit hyperactivity disorder (ADHD), yet discontinuation and switch to nonstimulant ADHD medications are common. This study aimed to identify genetic, clinical, and sociodemographic ...

Official Actions

September 2021

Reports to the Membership

Pages:865–879
Published Online:13 September 2021

https://doi.org/10.1176/appi.ajp.2021.178701

First Page
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