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American Journal of Psychiatry

Volume 172, Issue 3

March 2015

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Editorials

March 2015

Medications for First-Episode Psychosis: Making a Good Start

Lisa B. Dixon, M.D., M.P.H.
T. Scott Stroup, M.D., M.P.H.

Pages:209–211
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14111465

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March 2015

Genetic Investigation of Autism-Related Social Communication Deficits

Daniel B. Campbell, Ph.D.

Pages:212–213
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14121503

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March 2015

Amygdala Reactivity as Mental Health Risk Endophenotype: A Tale of Many Trajectories

J. Paul Hamilton, Ph.D.

Pages:214–215
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14121491

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March 2015

Failure Modes of the Will: From Goals to Habits to Compulsions?

Quentin J.M. Huys, M.B.B.S., Ph.D.
Frederike H. Petzschner, Ph.D.

Pages:216–218
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14121502

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Clinical Case Conference

March 2015

Improvement in Psychotic Symptoms After a Gluten-Free Diet in a Boy With Complex Autoimmune Illness

William W. Eaton, Ph.D.
Lian-Yu Chen, M.D.
F. Curtis Dohan, M.D.
Deanna L. Kelly, Pharm.D.
Nicola Cascella, M.D.

Pages:219–221
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14040550

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Perspectives in Global Mental Health

March 2015

Psychiatric Treatment of a Health Care Worker After Infection With Ebola Virus in Lagos, Nigeria

Abdulaziz Mohammed, M.B.B.S., M.P.H.-F.E
Taiwo Lateef Sheikh, M.B.B.S., M.S.C.
Saheed Gidado, M.B.B.S., M.P.H.-F.E.
Ismail Adeshina Abdus-salam, M.B.B.S., M.P.H.
Joseph Adeyemi, M.B.B.S., M.Sc.
Adebola Olayinka, M.B.B.S.
Chima Ohuabunwo, M.B.B.S.
Orina Oluwagbemiga Victor, M.S.W.
Patrick Nguku, M.B.B.S., M.P.H.
Erinfolami Adebayo Rasheed, M.B.B.S.
Funmi Doherty, M.S.W., M.P.H.
Ndadilnasiya Waziri, D.V.M., M.P.H.-FE
Faisal Shuaib, M.D., Dr.P.H.
Babalola Obafemi Joseph, M.B.B.S.
Idris Mohammed Bomai, D.V.M.
Akin Oyemakinde, M.B.B.S., M.P.H.

Pages:222–224
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14121576

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Images in Psychiatry

March 2015

The Artist, Depression, and the Mood Landscape

Vladimir Lerner, M.D., Ph.D.
Eliezer Witztum, M.D.

Pages:225–226
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14091159

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Reviews and Overviews

March 2015

Ovarian Hormone Fluctuation, Neurosteroids, and HPA Axis Dysregulation in Perimenopausal Depression: A Novel Heuristic Model

Jennifer L. Gordon, Ph.D.
Susan S. Girdler, Ph.D.
Samantha E. Meltzer-Brody, M.D.
Catherine S. Stika, M.D.
Rebecca C. Thurston, Ph.D.
Crystal T. Clark, M.D., M.Sc.
Beth A. Prairie, M.D.
Eydie Moses-Kolko, Ph.D.
Hadine Joffe, M.D., M.Sc.
Katherine L. Wisner, M.D., M.S.

Pages:227–236
Published Online:13 January 2015

https://doi.org/10.1176/appi.ajp.2014.14070918

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Objective:In this conceptual review, the authors propose a novel mechanistic candidate in the etiology of depression with onset in the menopause transition (“perimenopausal depression”) involving alterations in stress-responsive pathways, induced by ...

Articles

March 2015

Prescription Practices in the Treatment of First-Episode Schizophrenia Spectrum Disorders: Data From the National RAISE-ETP Study

Delbert G. Robinson, M.D.
Nina R. Schooler, Ph.D.
Majnu John, Ph.D.
Christoph U. Correll, M.D.
Patricia Marcy, B.S.N.
Jean Addington, Ph.D.
Mary F. Brunette, M.D.
Sue E. Estroff, Ph.D.
Kim T. Mueser, Ph.D.
David Penn, Ph.D.
James Robinson, M.Ed.
Robert A. Rosenheck, M.D.
Joanne Severe, M.S.
Amy Goldstein, Ph.D.
Susan Azrin, Ph.D.
Robert Heinssen, Ph.D.
John M. Kane, M.D.

Pages:237–248
Published Online:4 December 2014

https://doi.org/10.1176/appi.ajp.2014.13101355

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Objective:Treatment guidelines suggest distinctive medication strategies for first-episode and multiepisode patients with schizophrenia. To assess the extent to which community clinicians adjust their usual treatment regimens for first-episode patients, ...

March 2015

Outcomes of Nontransitioned Cases in a Sample at Ultra-High Risk for Psychosis

Ashleigh Lin, Ph.D.
Stephen J. Wood, Ph.D.
Barnaby Nelson, Ph.D.
Amanda Beavan, B.Sc.
Patrick McGorry, M.D., Ph.D., F.R.A.N.Z.C.P.
Alison R. Yung, M.D., F.R.A.N.Z.C.P.

Pages:249–258
Published Online:7 November 2014

https://doi.org/10.1176/appi.ajp.2014.13030418

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Objective:Two-thirds of individuals identified as at ultra-high risk for psychosis do not develop psychotic disorder over the medium term. The authors examined outcomes in a group of such patients.Method:Participants were help-seeking individuals ...

March 2015

IQ and Schizophrenia in a Swedish National Sample: Their Causal Relationship and the Interaction of IQ With Genetic Risk

Kenneth S. Kendler, M.D.
Henrik Ohlsson, Ph.D.
Jan Sundquist, M.D., Ph.D.
Kristina Sundquist, M.D., Ph.D.

Pages:259–265
Published Online:7 November 2014

https://doi.org/10.1176/appi.ajp.2014.14040516

Abstract
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Objective:The authors sought to clarify the relationship between IQ and subsequent risk for schizophrenia.Method:IQ was assessed at ages 18–20 in 1,204,983 Swedish males born between 1951 and 1975. Schizophrenia was assessed by hospital diagnosis through ...

March 2015

Social Responsiveness, an Autism Endophenotype: Genomewide Significant Linkage to Two Regions on Chromosome 8

Jennifer K. Lowe, Ph.D.
Donna M. Werling, Ph.D.
John N. Constantino, M.D.
Rita M. Cantor, Ph.D.
Daniel H. Geschwind, M.D., Ph.D.

Pages:266–275
Published Online:7 November 2014

https://doi.org/10.1176/appi.ajp.2014.14050576

Abstract
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Objective:Autism spectrum disorder is characterized by deficits in social function and the presence of repetitive and restrictive behaviors. Following a previous test of principle, the authors adopted a quantitative approach to discovering genes ...

March 2015

Developmental Change in Amygdala Reactivity During Adolescence: Effects of Family History of Depression and Stressful Life Events

Johnna R. Swartz, Ph.D.
Douglas E. Williamson, Ph.D.
Ahmad R. Hariri, Ph.D.

Pages:276–283
Published Online:19 December 2014

https://doi.org/10.1176/appi.ajp.2014.14020195

Abstract
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Objective:Although heightened amygdala reactivity is observed in patients with major depression, two critical gaps in our knowledge remain. First, it is unclear whether heightened amygdala reactivity is a premorbid vulnerability or a consequence of the ...

March 2015

Functional Neuroimaging of Avoidance Habits in Obsessive-Compulsive Disorder

Claire M. Gillan, Ph.D.
Annemieke M. Apergis-Schoute, Ph.D.
Sharon Morein-Zamir, Ph.D.
Gonzalo P. Urcelay, Ph.D.
Akeem Sule, M.B.B.S., M.R.C.Psych.
Naomi A. Fineberg, M.A., M.R.C.Psych.
Barbara J. Sahakian, Ph.D.
Trevor W. Robbins, Ph.D.

Pages:284–293
Published Online:19 December 2014

https://doi.org/10.1176/appi.ajp.2014.14040525

Abstract
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Objective:The purpose of this study was to determine the neural correlates of excessive habit formation in obsessive-compulsive disorder (OCD). The authors aimed to test for neurobiological convergence with the known pathophysiology of OCD and to infer, ...

Letters to the Editor

March 2015

Differential Effectiveness of Right Unilateral Versus Bilateral Electroconvulsive Therapy in Resistant Bipolar Depression

Georgios D. Kotzalidis, M.D., Ph.D.
Isabella Pacchiarotti, M.D., Ph.D.
Chiara Rapinesi, M.D.
Andrea Murru, M.D., Ph.D.
Francesc Colom, Psy.D.
Eduard Vieta, M.D., Ph.D.

Page:294
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14101366

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March 2015

Response to Kotzalidis et al.

Helle K. Schoeyen, M.D., Ph.D.
Ute Kessler, M.D., Ph.D.
Ole A. Andreassen, M.D., Ph.D.
Bjoern H. Auestad, Ph.D.
Per Bergsholm, M.D., Ph.D.
Ulrik F. Malt, M.D., Ph.D.
Gunnar Morken, M.D., Ph.D.
Ketil J Oedegaard, M.D., Ph.D.
Arne Vaaler, M.D., Ph.D.

Pages:294–295
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14101366r

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March 2015

Electroconvulsive Therapy Versus Pharmacotherapy for Bipolar Depression

Charles H. Kellner, M.D.
Max Fink, M.D.

Page:295
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14101284

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March 2015

Response to Kellner and Fink

Helle K. Schoeyen, M.D., Ph.D.
Ute Kessler, M.D., Ph.D.
Ole A. Andreassen, M.D., Ph.D.
Bjoern H. Auestad, Ph.D.
Per Bergsholm, M.D., Ph.D.
Ulrik F. Malt, M.D., Ph.D.
Gunnar Morken, M.D., Ph.D.
Ketil J Oedegaard, M.D., Ph.D.
Arne Vaaler, M.D., Ph.D.

Pages:295–296
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14101284r

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Book Forum

March 2015

History of Psychopharmacology, Volumes 1–4

Robert C. Smith, M.D., Ph.D.

Page:297
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2015.14121588

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March 2015

The Measure of Madness: Philosophy of Mind, Cognitive Neuroscience, and Delusional Thought

Dwight Dickinson, Ph.D., J.D.

Pages:297–298
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2014.14121521

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Books Received

March 2015

Pages:299–300
Published Online:1 March 2015

https://doi.org/10.1176/appi.ajp.2015.1723books

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