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American Journal of Psychiatry

Volume 172, Issue 2

February 2015

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Editorials

February 2015

Schizophrenia or Schizophrenias? The Challenge of Genetic Parsing of a Complex Disorder

Assen Jablensky, M.D., D.M.Sc.

Pages:105–107
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14111452

First Page
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February 2015

Getting to the Roots: Early Life Intervention and Adult Health

Ann Bullock, M.D.

Pages:108–110
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14111394

First Page
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February 2015

Piecing Together Mother’s Stress and Baby’s Genetics to Understand Brain Development

Jim Hudziak, M.D.

Pages:111–112
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14111453

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February 2015

The Affordable Care Act’s Dependent Coverage Provision and Young Adults With Psychiatric Disorders

Haiden A. Huskamp, Ph.D.

Pages:113–114
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14111395

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Treatment in Psychiatry

February 2015

Treatment of Psychosis and Mania in the Postpartum Period

Veerle Bergink, M.D., Ph.D.
Karin M. Burgerhout, M.D.
Kathelijne M. Koorengevel, M.D., Ph.D.
Astrid M. Kamperman, M.Sc., Ph.D.
Witte J. Hoogendijk, M.D., Ph.D.
Mijke P. Lambregtse-van den Berg, M.D., Ph.D.
Steven A. Kushner, M.D., Ph.D.

Pages:115–123
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.13121652

Abstract
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Postpartum psychosis is a severe disorder that warrants acute clinical intervention. Little is known, however, about what interventions are most effective. The authors present treatment response and remission outcomes at 9 months postpartum using a four-...

Reviews and Overviews

February 2015

Identifying Predictors, Moderators, and Mediators of Antidepressant Response in Major Depressive Disorder: Neuroimaging Approaches

Mary L. Phillips, M.D.
Henry W. Chase, Ph.D.
Yvette I. Sheline, M.D.
Amit Etkin, M.D., Ph.D.
Jorge R.C. Almeida, M.D., Ph.D.
Thilo Deckersbach, Ph.D.
Madhukar H. Trivedi, M.D.

Pages:124–138
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14010076

Abstract
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Objective:Despite significant advances in neuroscience and treatment development, no widely accepted biomarkers are available to inform diagnostics or identify preferred treatments for individuals with major depressive disorder.Method:In this critical ...

Articles

February 2015

Uncovering the Hidden Risk Architecture of the Schizophrenias: Confirmation in Three Independent Genome-Wide Association Studies

Javier Arnedo, M.S.
Dragan M. Svrakic, M.D., Ph.D.
Coral del Val, Ph.D.
Rocío Romero-Zaliz, Ph.D.
Helena Hernández-Cuervo, M.D.
Molecular Genetics of Schizophrenia Consortium
Ayman H. Fanous, M.D.
Michele T. Pato, M.D.
Carlos N. Pato, M.D., Ph.D.
Gabriel A. de Erausquin, M.D., Ph.D.
C. Robert Cloninger, M.D., Ph.D.
Igor Zwir, Ph.D.

Pages:139–153
Published Online:31 October 2014

https://doi.org/10.1176/appi.ajp.2014.14040435

Abstract
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Objective:The authors sought to demonstrate that schizophrenia is a heterogeneous group of heritable disorders caused by different genotypic networks that cause distinct clinical syndromes.Method:In a large genome-wide association study of cases with ...

February 2015

Paraprofessional-Delivered Home-Visiting Intervention for American Indian Teen Mothers and Children: 3-Year Outcomes From a Randomized Controlled Trial

Allison Barlow, M.P.H., Ph.D.
Britta Mullany, Ph.D., M.H.S.
Nicole Neault, M.P.H.
Novalene Goklish, B.S.
Trudy Billy, B.S.
Ranelda Hastings, B.S.
Sherilynn Lorenzo
Crystal Kee, B.S.
Kristin Lake, M.P.H.
Cleve Redmond, Ph.D.
Alice Carter, Ph.D.
John T. Walkup, M.D.

Pages:154–162
Published Online:31 October 2014

https://doi.org/10.1176/appi.ajp.2014.14030332

Abstract
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Objective:The Affordable Care Act provides funding for home-visiting programs to reduce health care disparities, despite limited evidence that existing programs can overcome implementation and evaluation challenges with at-risk populations. The authors ...

February 2015

COMT Haplotypes Modulate Associations of Antenatal Maternal Anxiety and Neonatal Cortical Morphology

Anqi Qiu, Ph.D.
Ta Anh Tuan, M.S.
Mei Lyn Ong, Ph.D.
Yue Li, B.S.
Helen Chen, M.D.
Anne Rifkin-Graboi, Ph.D.
Birit F.P. Broekman, M.D.
Kenneth Kwek, M.D.
Seang-Mei Saw, Ph.D.
Yap-Seng Chong, M.D.
Peter D. Gluckman, Ph.D.
Marielle V. Fortier, M.D.
Joanna Dawn Holbrook, Ph.D.
Michael J. Meaney, Ph.D.

Pages:163–172
Published Online:31 October 2014

https://doi.org/10.1176/appi.ajp.2014.14030313

Abstract
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Objective:Exposure to antenatal maternal anxiety and complex genetic variations may shape fetal brain development. In particular, the catechol-O-methyltransferase (COMT) gene, located on chromosome 22q11.2, regulates catecholamine signaling in the ...

February 2015

Feedback-Driven Trial-by-Trial Learning in Autism Spectrum Disorders

Marjorie Solomon, Ph.D.
Michael J. Frank, Ph.D.
J. Daniel Ragland, Ph.D.
Anne C. Smith, Ph.D.
Tara A. Niendam, Ph.D.
Tyler A. Lesh, Ph.D.
David S. Grayson, B.S.
Jonathan S. Beck, B.S.
John C. Matter, B.S.
Cameron S. Carter, M.D.

Pages:173–181
Published Online:31 October 2014

https://doi.org/10.1176/appi.ajp.2014.14010036

Abstract
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Objective:Impairments in learning are central to autism spectrum disorders. The authors investigated the cognitive and neural basis of these deficits in young adults with autism spectrum disorders using a well-characterized probabilistic reinforcement ...

February 2015

Effect of the Affordable Care Act’s Young Adult Insurance Expansions on Hospital-Based Mental Health Care

Ezra Golberstein, Ph.D.
Susan H. Busch, Ph.D.
Rebecca Zaha, M.P.H.
Shelly F. Greenfield, M.D., M.P.H.
William R. Beardslee, M.D.
Ellen Meara, Ph.D.

Pages:182–189
Published Online:31 October 2014

https://doi.org/10.1176/appi.ajp.2014.14030375

Abstract
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Objective:Insurance coverage for young adults has increased since 2010, when the Affordable Care Act (ACA) required insurers to permit children to remain on parental policies until age 26 as dependents. This study estimated the association between the ...

February 2015

Pleiotropic Locus for Emotion Recognition and Amygdala Volume Identified Using Univariate and Bivariate Linkage

Emma E.M. KnowlesPh.D.
D. Reese McKayPh.D.
Jack W. KentPh.D.
Emma SprootenPh.D.
Melanie A. CarlessPh.D.
Joanne E. CurranPh.D.
Marcio A.A. de AlmeidaPh.D.
Thomas D. DyerPh.D.
Harald H.H. GöringPh.D.
Rene L. Olvera, M.D.
Ravi DuggiralaPh.D.
Peter T. Fox, M.D.
Laura AlmasyPh.D.
John BlangeroPh.D.
David C. GlahnPh.D.

Pages:190–199
Published Online:31 October 2014

https://doi.org/10.1176/appi.ajp.2014.14030311

Abstract
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Objective:The role of the amygdala in emotion recognition is well established, and amygdala volume and emotion recognition performance have each been shown separately to be highly heritable traits, but the potential role of common genetic influences on ...

Letters to the Editor

February 2015

Maternal C-Reactive Protein and Schizophrenia

Jean-Paul Selten, M.D., Ph.D.
Jim van Os, M.D., Ph.D.

Page:200
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14101299

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February 2015

Response to Selten and van Os

Sarah Canetta, Ph.D.
Alan S. Brown, M.D., M.P.H.

Page:200
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14101299r

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February 2015

A New Role for Nortriptyline in Depression Associated With Vascular Disease?

Hagen Kunte, M.D.
Johannes Rentzsch, M.D.
Golo Kronenberg, M.D.

Page:201
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14070926

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February 2015

Response to Kunte et al.

Rudolf Uher, M.D., Ph.D.

Page:201
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14070926r

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February 2015

Mentally Ill in Prison Are Not Forgotten

Emil R. Pinta, M.D.

Pages:201–202
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14101294

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February 2015

Response to Pinta

David R. Rubinow, M.D.

Page:202
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14101294r

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Book Forum

February 2015

Fatal Pauses: Getting Unstuck Through the Power of No and the Power of Go

Roger Peele, M.D.
Raymond Crowel, Psy.D.

Pages:203–204
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14121481

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February 2015

Resilience and Aging: Research and Practice

Frank W. Brown, M.D.

Page:204
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2014.14111392

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Correction

February 2015

Page:204
Published Online:1 February 2015

https://doi.org/10.1176/appi.ajp.2015.1722correction

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