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American Journal of Psychiatry

Volume 167, Issue 5

May 2010

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In This Issue

May 2010

Page:A40
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.167.5.a40

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Editorial

May 2010

Personality Disorders in the Depressed: Seeing Clearly Through Blue Lenses

Robert Michels, M.D.

Pages:487–488
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10020172

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May 2010

Conflict Adaptation in Generalized Anxiety Disorder: Small Paradigm Twist, Large Scientific Leap

Monique Ernst, M.D., Ph.D.

Pages:489–492
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10010234

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May 2010

The Pharmacogenetics of Depression: Enter the GWAS

Anil K. Malhotra, M.D.

Pages:493–495
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10020244

First Page
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May 2010

Depression and Diabetes: More on What the Relationship Might Be

Constantine G. Lyketsos, M.D., M.H.S.

Pages:496–497
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10020243

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Commentary

May 2010

The Progression of Electronic Health Records and Implications for Psychiatry

Robert M. Plovnick, M.D., M.S.

Pages:498–500
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09101473

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Introspections

May 2010

Farewell, Moban

Geoffrey Neimark, M.D.

Page:501
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10010123

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Clinical Case Conference

May 2010

Neuropsychiatric Illness in Systemic Lupus Erythematosus: Insights From a Patient With Erotomania and Geschwind's Syndrome

Mark T. Wright, M.D.

Pages:502–507
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09040487

Abstract
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AbstractIndividuals suffering from systemic lupus erythematosus (SLE) can develop a number of psychiatric conditions, including psychosis. It is often unclear in SLE patients with psychiatric illness whether their illness is primary, due to SLE brain ...

Images in Psychiatry

May 2010

On Sorrow: Medical Advice From Ishaq ben Sulayman al-Israeli 1,000 Years Ago

Carlos E. Sluzki, M.D.

Page:508
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09091371

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Review and Overview

May 2010

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

Avshalom Caspi, Ph.D.,
Ahmad R Hariri, Ph.D.,
Andrew Holmes, Ph.D.,
Rudolf Uher, Ph.D., M.R.C.Psych., and
Terrie E. Moffitt, Ph.D.

Pages:509–527
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.09101452

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AbstractEvidence of marked variability in response among people exposed to the same environmental risk implies that individual differences in genetic susceptibility might be at work. The study of such Gene-by-Environment (GxE) interactions has gained ...

Article

May 2010

State Effects of Major Depression on the Assessment of Personality and Personality Disorder

Leslie C. Morey, Ph.D.,
M. Tracie Shea, Ph.D.,
John C. Markowitz, M.D.,
Robert L. Stout, Ph.D.,
Christopher J. Hopwood, Ph.D.,
John G. Gunderson, M.D.,
Carlos M. Grilo, Ph.D.,
Thomas H. McGlashan, M.D.,
Shirley Yen, Ph.D.,
Charles A. Sanislow, Ph.D., and
Andrew E. Skodol, M.D.

Pages:528–535
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09071023

Abstract
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ObjectiveThe authors sought to determine whether personality disorders diagnosed during a depressive episode have long-term outcomes more typical of those of other patients with personality disorders or those of patients with noncomorbid major depression. ...

May 2010

Automatic and Strategic Representation of the Self in Major Depression: Trait and State Abnormalities

Avgusta Y. Shestyuk, Ph.D., and
Patricia J. Deldin, Ph.D.

Pages:536–544
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.06091444

Abstract
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ObjectiveDysfunctional negative thoughts about the self have long been hypothesized to reflect mood-independent cognitive vulnerability for major depressive disorder. These thoughts are believed to be predominantly automatic, in that they are involuntary ...

May 2010

Failure of Anterior Cingulate Activation and Connectivity With the Amygdala During Implicit Regulation of Emotional Processing in Generalized Anxiety Disorder

Amit Etkin, M.D., Ph.D.,
Katherine E. Prater, B.A.,
Fumiko Hoeft, M.D., Ph.D.,
Vinod Menon, Ph.D., and
Alan F. Schatzberg, M.D.

Pages:545–554
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09070931

Abstract
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ObjectiveClinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors ...

May 2010

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

Rudolf Uher, M.D., Ph.D., M.R.C.Psych.,
Nader Perroud, M.D.,
Mandy Y.M. Ng, Ph.D.,
Joanna Hauser, Ph.D.,
Neven Henigsberg, M.D.,
Wolfgang Maier, M.D.,
Ole Mors, Ph.D.,
Anna Placentino, Psy.D.,
Marcella Rietschel, M.D.,
Daniel Souery, Ph.D.,
Tina Žagar, Ph.D.,
Piotr M. Czerski, Ph.D.,
Borut Jerman, B.Sc.,
Erik Roj Larsen, M.D., Ph.D.,
Thomas G. Schulze, M.D.,
Astrid Zobel, M.D.,
Sarah Cohen-Woods, Ph.D.,
Katrina Pirlo, B.Sc.,
Amy W. Butler, Ph.D.,
Pierandrea Muglia, M.D.,
Michael R. Barnes, Ph.D.,
Mark Lathrop<, Ph.D.,
Anne Farmer, M.D., F.R.C.Psych.,
Gerome Breen, Ph.D.,
Katherine J. Aitchison, M.D., M.R.C.Psych., Ph.D.,
Ian Craig, Ph.D.,
Cathryn M. Lewis, Ph.D., and
Peter McGuffin, F.R.C.P., F.R.C.Psych., Ph.D.

Pages:555–564
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09070932

Abstract
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ObjectiveThe purpose of this study was to identify genetic variants underlying the considerable individual differences in response to antidepressant treatment. The authors performed a genome-wide association analysis of improvement of depression severity ...

May 2010

Association of Mu-Opioid Receptor Variants and Response to Citalopram Treatment in Major Depressive Disorder

Holly A. Garriock, Ph.D.,
Michael Tanowitz, Ph.D.,
Jeffrey B. Kraft, Ph.D.,
Vu C. Dang, Ph.D.,
Eric J. Peters, Ph.D.,
Greg D. Jenkins, M.S.,
Megan S. Reinalda, B.S.,
Patrick J. McGrath, M.D.,
Mark von Zastrow, M.D., Ph.D.,
Susan L. Slager, Ph.D., and
Steven P. Hamilton, M.D., Ph.D.

Pages:565–573
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.08081167

Abstract
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ObjectiveBecause previous preclinical and clinical studies have implicated the endogenous opioid system in major depression and in the neurochemical action of antidepressants, the authors examined how DNA variation in the μ-opioid receptor gene may ...

May 2010

Prevalence of Incompletely Penetrant Huntington's Disease Alleles Among Individuals With Major Depressive Disorder

Roy H. Perlis, M.D., M.Sc.,
Jordan W. Smoller, M.D., Sc.D.,
Jayalakshmi Mysore,
Mei Sun, Ph.D.,
Tammy Gillis,
Shaun Purcell, Ph.D.,
Marcella Rietschel, M.D.,
Markus M. Nöthen, M.D.,
Stephanie Witt, Ph.D.,
Wolfgang Maier, M.D.,
Dan V. Iosifescu, M.D., M.Sc.,
Patrick Sullivan, M.D.,
A. John Rush, M.D.,
Maurizio Fava, M.D.,
Hans Breiter, M.D.,
Marcy Macdonald, Ph.D., and
James Gusella, Ph.D.

Pages:574–579
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09070973

Abstract
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ObjectivePresymptomatic individuals with the Huntingtin (HTT) CAG expansion mutation that causes Huntington's disease may have higher levels of depressive symptoms than healthy comparison populations. However, the prevalence of HTT CAG repeat expansions ...

May 2010

Depressive Disorder and Incident Diabetes Mellitus: The Effect of Characteristics of Depression

Antonio Campayo, M.D.,
Peter de Jonge, Ph.D.,
Juan F Roy, Ph.D.,
Pedro Saz, M.D., Ph.D.,
Concepción de la Cámara, M.D., Ph.D.,
Miguel A. Quintanilla, M.D., Ph.D.,
Guillermo Marcos, M.D., Ph.D.,
Javier Santabárbara, M.S., and
Antonio Lobo, M.D., Ph.D.

Pages:580–588
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09010038

Abstract
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ObjectiveThe purpose of this study was to test the hypothesis that clinically significant depression detected in a population sample increases the risk of diabetes mellitus. The authors examined the effect of characteristics of depression frequently found ...

May 2010

Association of Depressed Mood and Mortality in Older Adults With and Without Cognitive Impairment in a Prospective Naturalistic Study

Helen Lavretsky, M.D.,
Ling Zheng, M.B.B.S., Ph.D.,
Michael W. Weiner, M.D.,
Dan Mungas, Ph.D.,
Bruce Reed, Ph.D.,
Joel H. Kramer, Psy.D.,
William Jagust, M.D.,
Helena Chui, M.D., and
Wendy J. Mack, Ph.D.

Pages:589–597
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09020280

Abstract
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ObjectiveThe authors examined predictors of mortality in individuals age 50 or older with or without cognitive impairment in a 12-year prospective naturalistic study of subcortical ischemic vascular disease focusing on symptoms of depressed mood, apathy, ...

Letter to the Editor

May 2010

Psychosis Associated With Medical Marijuana: Risk vs. Benefits of Medicinal Cannabis Use

Joseph M. Pierre, M.D.

Pages:598–599
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.09121762

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May 2010

Scientifically Unfounded Claims in Diagnosing and Treating Patients

Bryon Adinoff, M.D., and
Michael Devous, Ph.D.

Page:598
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10020157

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May 2010

Do Antidepressants Alter Emotional Processing in PTSD?

Robert Hierholzer, M.D.

Page:599
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.09121733

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May 2010

Drs. Harmer, Goodwin, and Cowen Reply

Catherine J. Harmer, D.Phil.,
Guy M. Goodwin, D.Phil., F.R.C.Psych., and
Philip J. Cowen, M.D., F.R.C.Psych.

Pages:599–600
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.09121733r

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May 2010

Dazed and Confused by Self-Medication

R. Andrews Chambers, M.D.

Page:600
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10010099

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May 2010

Dr. Hien Replies

Denise A. Hien, Ph.D.

Pages:600–601
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10010099r

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May 2010

Anorexia Nervosa: A Single Region of Interest for Self-Referent Processing of Pictures of Body Images?

Charlotte Keating, B.B.N.Sc., (P.G.Dip.Psych.)

Pages:601–602
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.09121712

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May 2010

Clozapine Rechallenge in Refractory Schizophrenia

Chikezie Eseonu, B.A., and
Jon Carlson, M.D.

Pages:602–603
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09111560

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May 2010

Drs. Fladung, Herrnberger, and Grön Reply

Anne-Katharina Fladung, Ph.D.,
Bärbel Herrnberger, Ph.D., and
Georg Grön, Ph.D.

Page:602
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.09121712r

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Book Forum

May 2010

The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th ed.

Helen C. Kales, M.D.

Page:604
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09091340

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May 2010

Disparities in Psychiatric Care: Clinical and Cross-Cultural Perspectives

Douglas K. Novins, M.D.

Page:605
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09111684

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May 2010

Understanding Body Dysmorphic Disorder: An Essential Guide

Lisa A. Mellman, M.D.

Page:606
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09111701

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May 2010

Textbook of Anxiety Disorders, 2nd ed.

Robert E. Feinstein, M.D.

Pages:606–607
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.09121838

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May 2010

The Madness Within Us: Schizophrenia as a Neuronal Process

Jack D. Barchas, M.D.

Pages:607–609
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2010.10020270

First Page
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Books Received

May 2010

Page:610
Published Online:1 May 2010

https://doi.org/10.1176/appi.ajp.2009.167.5.610

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