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American Journal of Psychiatry

Volume 169, Issue 3

March 2012

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In This Issue

March 2012

Page:A22
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2012.169.3.a22

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Editorial

March 2012

Diagnosing Personality Disorders

Robert Michels, M.D.

Pages:241–243
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11121839

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March 2012

How Good Are Observational Studies in Assessing Psychiatric Treatment Outcomes?

T. Michael Kashner, Ph.D., J.D.

Pages:244–247
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2012.12010005

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March 2012

Are Adults Just Big Children?

Graham J. Emslie, M.D.

Pages:248–250
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2012.12010004

First Page
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March 2012

Silent Cerebrovascular Events and Alzheimer's Disease: An Overlooked Opportunity for Prevention?

P. Murali Doraiswamy, M.B.B.S., F.R.C.P.

Pages:251–254
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11121830

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Images in Psychiatry

March 2012

Zoroastrian Priests: Ancient Persian Psychiatrists

Arman Zargaran, Pharm.D.,
Alireza Mehdizadeh, M.D., Ph.D.,
Hassan Yarmohammadi, and
Abdolali Mohagheghzadeh, Pharm.D., Ph.D.

Page:255
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11081185

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Treatment in Psychiatry

March 2012

The Effect of Gastric Bypass on the Pharmacokinetics of Serotonin Reuptake Inhibitors

Giselle G. Hamad, M.D.,
Joseph C. Helsel, B.S.,
James M. Perel, Ph.D.,
Gina M. Kozak, P.A.-C.,
Mary C. McShea, M.S.,
Carolyn Hughes, M.S.W.,
Andrea L. Confer, B.A.,
Dorothy K. Sit, M.D.,
Carol A. McCloskey, M.D., and
Katherine L. Wisner, M.D., M.S.

Pages:256–263
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11050719

Abstract
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Morbidly obese patients treated with serotonin reuptake inhibitors for mood and anxiety disorders frequently relapse following gastric bypass surgery. Of 12 patients followed, drug absorption 1 month postoperatively dropped to an average of 54% of ...

Reviews and Overviews

March 2012

Striatal Dopamine Transporter Alterations in ADHD: Pathophysiology or Adaptation to Psychostimulants? A Meta-Analysis

Paolo Fusar-Poli, Ph.D.,
Katya Rubia, Ph.D.,
Giorgio Rossi, M.D.,
Giuseppe Sartori, Ph.D., and
Umberto Balottin, M.D., Ph.D.

Pages:264–272
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11060940

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Background:Striatal dopamine transporter abnormalities are thought to underlie the pathophysiology and psychostimulant treatment of attention deficit hyperactivity disorder (ADHD). However, individual studies using single photon emission tomography (SPECT)...

Articles

March 2012

An Empirically Derived Taxonomy for Personality Diagnosis: Bridging Science and Practice in Conceptualizing Personality

Drew Westen, Ph.D.,
Jonathan Shedler, Ph.D.,
Bekh Bradley, Ph.D., and
Jared A. DeFife, Ph.D.

Pages:273–284
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11020274

Abstract
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Objective:The authors describe a system for diagnosing personality pathology that is empirically derived, clinically relevant, and practical for day-to-day use. Method:A random national sample of psychiatrists and clinical psychologists (N=1,201) ...

March 2012

Antiepileptic Drugs for Bipolar Disorder and the Risk of Suicidal Behavior: A 30-Year Observational Study

Andrew C. Leon, Ph.D.,
David A. Solomon, M.D.,
Chunshan Li, M.A.,
Jess G. Fiedorowicz, M.D.,
William H. Coryell, M.D.,
Jean Endicott, Ph.D., and
Martin B. Keller, M.D.

Pages:285–291
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11060948

Abstract
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The FDA in 2009 warned of increased suicidality with all antiepileptic drugs, regardless of the illness being treated. Longitudinal clinical observations of 199 bipolar patients taking carbamazepine, lamotrigine, or valproate in five U.S. medical centers ...

March 2012

A Double-Blind Placebo-Controlled Trial of Fluoxetine for Repetitive Behaviors and Global Severity in Adult Autism Spectrum Disorders

Eric Hollander, M.D.,
Latha Soorya, Ph.D.,
William Chaplin, Ph.D.,
Evdokia Anagnostou, M.D.,
Bonnie P. Taylor, Ph.D.,
Casara J. Ferretti, M.S.,
Stacey Wasserman, M.D.,
Erika Swanson, M.A., and
Cara Settipani, B.A.

Pages:292–299
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.10050764

Abstract
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Objective:The effects of fluoxetine and placebo on repetitive behaviors and global severity were compared in adults with autism spectrum disorders (ASDs). Method:Adults with ASDs were enrolled in a 12-week double-blind placebo-controlled fluoxetine trial. ...

March 2012

Association of Cerebral Emboli With Accelerated Cognitive Deterioration in Alzheimer's Disease and Vascular Dementia

Nitin Purandare, Ph.D., F.R.C.Psych.,
Alistair Burns, M.D., F.R.C.Psych.,
Julie Morris, M.Sc.,
Ewan P. Perry, Ph.D.,
Joanne Wren, B.Sc., and
Charles McCollum, M.D., F.R.C.S.

Pages:300–308
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11010009

Abstract
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Transcranial Doppler imaging found middle cerebral artery emboli in nearly half of patients with either vascular or Alzheimer's dementia. Patients with emboli had more rapid progression of dementia over 2 years than those who were emboli free, and their ...

March 2012

The Interaction of Parental History of Suicidal Behavior and Exposure to Adoptive Parents' Psychiatric Disorders on Adoptee Suicide Attempt Hospitalizations

Holly C. Wilcox, Ph.D.,
S. Janet Kuramoto, Ph.D., M.H.S.,
David Brent, M.D., and
Bo Runeson, M.D., Ph.D.

Pages:309–315
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11060890

Abstract
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Objective:The authors examined the risk of suicide attempt or other psychiatric hospitalization among adoptees whose biological parents died from or were hospitalized for suicidal behavior (BPSB) relative to adoptees whose biological parents had a ...

March 2012

Increased Medial Orbitofrontal and Amygdala Activation: Evidence for a Systems-Level Endophenotype of Bipolar I Disorder

Julia Linke, M.S.,
Andrea Victoria King, M.S.,
Marcella Rietschel, M.D.,
Jana Strohmaier, M.S.,
Michael Hennerici, M.D.,
Achim Gass, M.D.,
Andreas Meyer-Lindenberg, M.D., Ph.D., and
Michèle Wessa, Ph.D.

Pages:316–325
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11050711

Abstract
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Objective:Bipolar I disorder is highly heritable, but endophenotypes of the disorder mediating genetic risk are only beginning to be defined. The authors investigate state- and trait-related neural mechanisms related to motivation in euthymic bipolar ...

March 2012

Lower β₂*-Nicotinic Acetylcholine Receptor Availability in Smokers With Schizophrenia

Deepak Cyril D'Souza, M.D.,
Irina Esterlis, Ph.D.,
Michelle Carbuto, B.A.,
Maegan Krasenics, B.A.,
John Seibyl, M.D.,
Frederic Bois, Ph.D.,
Brian Pittman, M.S.,
Mohini Ranganathan, M.D.,
Kelly Cosgrove, Ph.D., and
Julie Staley, Ph.D.

Pages:326–334
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11020189

Abstract
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Objective:There is a strong association between cigarette smoking and schizophrenia. Nicotine's actions in the brain are mediated through nicotinic acetylcholine receptors. Those containing α₄ and β₂ subunits are the most abundant ones in the brain, have ...

Letters to the Editor

March 2012

Five New Schizophrenia Loci May Converge on the Same Cellular Mechanism: The AKT Pathway

Zsolt Balog, Ph.D.,
Imre Kiss, M.D., and
Szabolcs Kéri, M.D., Ph.D., D.Sc.

Page:335
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11101562

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Book Forum

March 2012

Handbook of Mentalizing in Mental Health Practice

Lois W. Choi-Kain, M.D.

Page:336
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11101525

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March 2012

Researching the Autism Spectrum: Contemporary Perspectives

Susan Hepburn, Ph.D.

Page:337
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11101504

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March 2012

Trichotillomania, Skin Picking, and Other Body-Focused Repetitive Behaviors

Joseph Zohar, M.D., and
Oded Ben-Arush, Ph.D.

Pages:337–338
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11101505

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March 2012

Disaster Psychiatry: Readiness, Evaluation, and Treatment

Linda Piwowarczyk, M.D., M.P.H.

Page:338
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2011.11101506

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Correction

March 2012

Page:338
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2012.169.3.338

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Books Received

March 2012

Page:339
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2012.169.3.339

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APA Official Actions

March 2012

Psychiatric Violence Risk Assessment

Alec Buchanan, M.D., Ph.D.,
Renee Binder, M.D.,
Michael Norko, M.D., and
Marvin Swartz, M.D.

Page:340
Published Online:1 March 2012

https://doi.org/10.1176/appi.ajp.2012.169.3.340

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