Metformin for Treatment of Antipsychotic-Induced Amenorrhea and Weight Gain in Women With First-Episode Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled Study
- Ren-Rong Wu,
M.D., Ph.D. , - Hua Jin,
M.D. , - Keming Gao,
M.D., Ph.D. , - Elizabeth W. Twamley,
Ph.D. , - Jian-Jun Ou,
M.D. , - Ping Shao,
M.D. , - Juan Wang,
M.D. , - Xiao-Feng Guo,
M.D., Ph.D. , - John M. Davis,
M.D. , - Philip K. Chan,
M.S. , and - Jing-Ping Zhao,
M.D., Ph.D.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
From the Institute of Mental Health of the Second Xiangya Hospital, Central South University, Changsha, China; the Department of Psychiatry, University of California, San Diego, La Jolla; the Department of Psychiatry, Case Western Reserve and University Hospital Case Medical Center, Cleveland; the Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego; the Department of Psychiatry, University of Illinois at Chicago; and the Hangzhou Seventh People Hospital, Hangzhou, China.
Supplemental Material
appi.ajp.2012.11091432.ds001.pdf (86 KB)