Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Articles   |    
Computer EEG and Auditory Evoked Potential Investigations in Children at High Risk for Schizophrenia
Am J Psychiatry 1974;131:892-900.
View Author and Article Information

Research Professor and Director, Division of Biological Psychiatry, New York Medical College, 106th St. and Fifth Ave., New York, N.Y. 10029

Senior Systems Analyst, Chrysler Corp., St. Louis, Mo.

Research Fellow, St. Louis State Hospital, St. Louis, Mo.

Director, Psykologisk Institut, Copenhagen, Denmark

1974, The American Psychiatric Association

text A A A
PDF of the full text article.

Computerized EEG and evoked auditory potential investigations demonstrated that the patterns of a group of children at high risk for schizophrenia (children of schizophrenic parents) had statistically significant differences when compared with those of a matched control group of children. High-risk children were characterized by the presence of high-frequency beta activity, fewer fast alpha waves, and more very slow low-voltage delta activity in computerized EEG as well as by shorter latencies in auditory evoked potential. These neurophysiological characteristics of high-risk children showed striking similarities to computerized EEG and evoked potential findings in psychotic children and schizophrenic adults, suggesting that this pattern may be the neurophysiological measurement of schizophrenia. These findings support some of the most recent biochemical hypotheses in schizophrenia and, if confirmed by further work, suggest new means in the preventive treatment of this illness.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).




CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe

Web of Science® Times Cited: 59

Related Content
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 27.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 7.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 52.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 8.  >
DSM-5™ Handbook of Differential Diagnosis > Chapter 2.  >
Topic Collections
Psychiatric News
APA Guidelines
PubMed Articles