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American Journal of Psychiatry

Volume 171, Issue 1

January 2014

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In This Issue

January 2014

Page:A30
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.17101issue

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Editorials

January 2014

Treatment in Nonresponsive Patients With Social Anxiety: Back to the Future With Benzodiazepines

Peter Roy-Byrne, M.D.

Pages:1–4
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13101304

First Page
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January 2014

Autism and Specific Language Impairment: To Know What We See, or How Your Sample Determines What You Observe

Young Shin Kim, M.D., M.S., M.P.H., Ph.D.

Pages:5–8
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13101379

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January 2014

Zeroing In on Early Cognitive Development in Schizophrenia

Dwight Dickinson, J.D., Ph.D.

Pages:9–12
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13101303

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January 2014

Psychoanalysis or Cognitive-Behavioral Therapy for Bulimia Nervosa: the Specificity of Psychological Treatments

Steven D. Hollon, Ph.D., and

G. Terence Wilson, Ph.D.

Pages:13–16
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13101302

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Commentary

January 2014

Cardiac Safety Concerns Remain for Citalopram at Dosages Above 40 mg/Day

Steven T. Bird, Pharm.D., M.S.,
Victor Crentsil, M.D.,
Robert Temple, M.D.,
Simone Pinheiro, Sc.D., M.Sc.,
Dorothy Demczar, Pharm.D., and
Marc Stone, M.D.

Pages:17–19
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13070905

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January 2014

Safety of High-Dosage Citalopram

Kara Zivin, Ph.D.,
Paul N. Pfeiffer, M.D.,
Amy S.B. Bohnert, Ph.D.,
Dara Ganoczy, M.P.H.,
Frederic C. Blow, Ph.D.,
Brahmajee K. Nallamothu, M.D., and
Helen C. Kales, M.D.

Pages:20–22
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13081052

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Introspection

January 2014

Allen Ginsberg’s Kind of Psychiatrist

Stevan Weine, M.D.

Pages:23–24
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13081084

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Clinical Case Conference

January 2014

Schizophrenia Complicated by Chronic Hepatitis C Virus and Hepatic Encephalopathy

Mark Viron, M.D.,
Adam Philip Stern, M.D., and
Matcheri S. Keshavan, M.D.

Pages:25–31
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13020238

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Images in Psychiatry

January 2014

Concerns About the Heritability of Serious Mental Illness: A Not-So-Strange Interlude

Gregory Costain, Ph.D.

Pages:32–33
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13060842

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Reviews and Overviews

January 2014

Childhood Separation Anxiety and the Pathogenesis and Treatment of Adult Anxiety

Barbara Milrod, M.D.,
John C. Markowitz, M.D.,
Andrew J. Gerber, M.D., Ph.D.,
Jill Cyranowski, Ph.D.,
Margaret Altemus, M.D.,
Theodore Shapiro, M.D.,
Myron Hofer, M.D., and
Charles Glatt, M.D.

Pages:34–43
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13060781

Abstract
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Psychotherapies focusing on relationships and separation anxiety may be helpful for adults with anxiety disorders who experienced separation anxiety in childhood. The fear extinction model of anxiety calls for desensitization to threatening stimuli and ...

Articles

January 2014

A Double-Blind Randomized Controlled Trial of Augmentation and Switch Strategies for Refractory Social Anxiety Disorder

Mark H. Pollack, M.D.,
Michael Van Ameringen, M.D.,
Naomi M. Simon, M.D., M.Sc.,
John W. Worthington, M.D.,
Elizabeth A. Hoge, M.D.,
Aparna Keshaviah, Sc.M., and
Murray B. Stein, M.D., M.P.H.

Pages:44–53
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.12101353

Abstract
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Adding clonazepam increases the likelihood of response in patients with social anxiety disorder who remain symptomatic after a trial with an SSRI, supporting the common clinical practice of combining a benzodiazepine with an SSRI. Among 181 nonresponders ...

January 2014

Short-Term Use of Serotonin Reuptake Inhibitors and Risk of Upper Gastrointestinal Bleeding

Yen-Po Wang, M.D.,
Yung-Tai Chen, M.D.,
Chia-Fen Tsai, M.D.,
Szu-Yuan Li, M.D.,
Jiing-Chyuan Luo, M.D.,
Shuu- Jiun Wang, M.D.,
Chao-Hsiun Tang, Ph.D.,
Chia-Jen Liu, M.D.,
Han-Chieh Lin, M.D.,
Fa-Yauh Lee, M.D.,
Full-Young Chang, M.D., and
Ching-Liang Lu, M.D.

Pages:54–61
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.12111467

Abstract
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Short-term SSRI use—even as little as 7 days—elevated the risk of upper gastrointestinal bleeding, especially in male patients. Just as with NSAIDs and aspirin, physicians should carefully monitor for this side effect.

January 2014

Lower Gene Expression for KCNS3 Potassium Channel Subunit in Parvalbumin-Containing Neurons in the Prefrontal Cortex in Schizophrenia

Danko Georgiev, M.D., Ph.D.,
Dominique Arion, Ph.D.,
John F. Enwright, Ph.D.,
Mitsuru Kikuchi, M.D., Ph.D.,
Yoshio Minabe, M.D., Ph.D.,
John P. Corradi, Ph.D.,
David A. Lewis, M.D., and
Takanori Hashimoto, M.D., Ph.D.

Pages:62–71
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13040468

Abstract
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ObjectiveIn schizophrenia, alterations in markers of cortical GABA neurotransmission are prominent in parvalbumin-containing neurons. Parvalbumin neurons selectively express KCNS3, the gene encoding the Kv9.3 potassium channel α-subunit. Kv9.3 subunits ...

January 2014

A Genome Scan for Loci Shared by Autism Spectrum Disorder and Language Impairment

Christopher W. Bartlett, Ph.D.,
Liping Hou, Ph.D.,
Judy F. Flax, Ph.D.,
Abby Hare, B.S.,
Soo Yeon Cheong, Ph.D.,
Zena Fermano, M.A.,
Barbie Zimmerman-Bier, M.D.,
Charles Cartwright, M.D.,
Marco A. Azaro, Ph.D.,
Steven Buyske, Ph.D., and
Linda M. Brzustowicz, M.D.

Pages:72–81
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.12081103

Abstract
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A study of 79 families with one child with autism and at least one child with a language impairment revealed a possible genetic connection between autism in children and language problems in other family members. Genes in a narrow region of two ...

January 2014

The Neural Correlates of Anomalous Habituation to Negative Emotional Pictures in Borderline and Avoidant Personality Disorder Patients

Harold W. Koenigsberg, M.D.,
Bryan T. Denny, Ph.D.,
Jin Fan, Ph.D.,
Xun Liu, Ph.D.,
Stephanie Guerreri,
Sarah Jo Mayson,
Liza Rimsky,
Antonia S. New, M.D.,
Marianne Goodman, M.D., and
Larry J. Siever, M.D.

Pages:82–90
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13070852

Abstract
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Failure to attain emotional habituation may contribute to the rapidly and abruptly shifting moods that characterize borderline personality disorder. The absence of increased dorsal anterior cingulate activity during habituation to negative pictures was ...

January 2014

Neuropsychological Decline in Schizophrenia From the Premorbid to the Postonset Period: Evidence From a Population-Representative Longitudinal Study

Madeline H. Meier, Ph.D.,
Avshalom Caspi, Ph.D.,
Abraham Reichenberg, Ph.D.,
Richard S.E. Keefe, Ph.D.,
Helen L. Fisher, Ph.D.,
HonaLee Harrington, B.S.,
Renate Houts, Ph.D.,
Richie Poulton, Ph.D., and
Terrie E. Moffitt, Ph.D.

Pages:91–101
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.12111438

Abstract
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ObjectiveDespite the widespread belief that neuropsychological decline is a cardinal feature of the progression from the premorbid stage to the chronic form of schizophrenia, few longitudinal studies have examined change in neuropsychological functioning ...

January 2014

Patient Personality and Therapist Response: An Empirical Investigation

Antonello Colli, Ph.D.,
Annalisa Tanzilli, Ph.D.,
Giancarlo Dimaggio, M.D., and
Vittorio Lingiardi, M.D.

Pages:102–108
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13020224

Abstract
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ObjectiveThe aim of this study was to examine the relationship between therapists’ emotional responses and patients’ personality disorders and level of psychological functioning.MethodA random national sample of psychiatrists and clinical psychologists (N=...

January 2014

A Randomized Controlled Trial of Psychoanalytic Psychotherapy or Cognitive-Behavioral Therapy for Bulimia Nervosa

Stig Poulsen, Ph.D.,
Susanne Lunn, M.Sc.,
Sarah I. F. Daniel, Ph.D.,
Sofie Folke, M.Sc.,
Birgit Bork Mathiesen, Ph.D.,
Hannah Katznelson, M.Sc., and
Christopher G. Fairburn, F.Med.Sci., F.R.C.Psych.

Pages:109–116
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.12121511

Abstract
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Two years of psychoanalytic psychotherapy and 5 months of CBT with follow up visits for bulimia nervosa were compared. The proportions of patients who had stopped binging and purging at 2 years were 15% for psychoanalytic psychotherapy and 44% for CBT. ...

Letters to the Editor

January 2014

High Dosages of Antidepressants Prescribed Without Risk?

Shuai-Ting Lin, M.D.,
Cheng-Chung Chen, M.D., Ph.D., and
Hin-Yeung Tsang, M.R.C.Psych., Ph.D.

Pages:117–118
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13050632

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January 2014

Diffusion of Prazosin Treatment for PTSD

Eric Hermes, M.D.,

Ilan Harpaz-Rotem, Ph.D., and

Robert Rosenheck, M.D.

Page:117
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13091259

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January 2014

Adequate Dosing for Second-Generation Antipsychotics in Establishing Treatment Resistance in Schizophrenia

Jimmy Lee, M.B.B.S, M.Med., and
Gary Remington, M.D., Ph.D.

Pages:118–119
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13070965

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January 2014

Metformin and Alzheimer’s Disease Risk

Jonathan E. Rosenfeld, M.D., Ph.D.

Page:119
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13091193

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January 2014

Response to Rosenfeld

L. Fredrik Jarskog, M.D., and
T. Scott Stroup, M.D., M.P.H.

Pages:119–120
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13091193r

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Correction

January 2014

Page:120
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.17101

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Book Forum

January 2014

Learning to Listen: A Life Caring for Children

Michael Jellinek, M.D.

Pages:121–122
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13050600

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January 2014

The Nature of Healing: The Modern Practice of Medicine

Nicholas Kontos, M.D.

Pages:122–123
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13030429

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January 2014

Psycho-Oncology

Donna Greenberg, M.D.

Pages:123–124
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13081098

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January 2014

Cognitive-Behavior Therapy for Children and Adolescents

Betsy D. Kennard, Psy.D.

Page:124
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.13081144

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Books Received

January 2014

Page:125
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.17101books

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Editor Disclosures

January 2014

Disclosure of Financial Relationships

Page:126
Published Online:1 January 2014

https://doi.org/10.1176/appi.ajp.2013.17101126

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