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EFFECT OF VARIOUS MODES OF ADMINISTRATION OF INSULIN ON THE HYPOGLYCEMIA IN PATIENTS UNDERGOING INSULIN SHOCK THERAPY

Published Online:https://doi.org/10.1176/ajp.99.5.698

The production of hypoglycemic coma by the intravenous use of insulin required essentially the same amounts of insulin as the intramuscular route. The onset of coma occurred earlier after intravenous insulin injection. The administration of insulin in divided doses both intravenously and intramuscularly reduced the amounts required to produce hypoglycemic coma, and reduced the number of days required to produce the initial coma.

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