Long-Term Prognosis and the Response of Schizophrenic Children to Drug Therapy : A Controlled Study of Trifluoperazine
Abstract
Previous studies have demonstrated that severity of language impairment is a critical determinant of long-term outcome for schizophrenic children in the age group of two to six years. Language impairment was therefore used as the major measure of severity in this study, designed to test whether subgroups of schizophrenic children, divided according to prognostic criteria, would respond differently to drugs as well as to placebo. Responses to both nonpharmacologic aspects of treatment and to the drug itself were found to be related to the initial severity of language impairment. Thus the major developmental defect determining long-term outcome for schizophrenic children in this age group also predicted the immediate responsiveness to treatment.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).