A METHOD OF EVALUATING A THERAPEUTIC AGENT
Abstract
1. A method of evaluating a therapeutic agent in psychiatric disorders is described. [see Tabel 1 in source pdf]
2. Advantages and disadvantages of such a method are discussed.
3. This method is used in a study of the effects of dibenamine in 30 patients suffering from various psychiatric disorders.
4. It is demonstrated that in the dosage used dibenamine is not more effective than a placebo in the care of patients as described.
5. Nausea and vomiting occurred in 11 of 30 patients receiving dibenamine, as against 2 receiving placebo.
6. An increase of symptoms was found in 3 of 5 depressed patients receiving dibenamine.
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