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Published Online:https://doi.org/10.1176/ajp.101.6.789

The use of demerol hydrochloride in 22 cases receiving artificial fever therapy in the Kettering hypertherm is reported. This represented a total of 165 treatments. The youngest patient was seventeen years and the oldest was sixty-five years of age.

Treatments were usually given at weekly intervals with the temperature maintained between 105 and 107 degrees Fahrenheit for three to five hours.

In 5 cases there was opportunity to compare demerol with the use of other drugs. In all such clinical comparisons demerol was found to be superior from a standpoint of management, safety and comfort of the patient. [See table In Source PDF].

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