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American Journal of Psychiatry

Volume 179, Issue 12

December 2022

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Editor’s Note

December 2022

New Therapeutic Approaches Involving Psychopharmacology, Digital Technology, and fMRI Neurofeedback

Ned H. Kalin, M.D.

Pages:881–885
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.20220866

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Editorials

December 2022

Naltrexone and Alcohol Use

Jonathan Avery, M.D.

Pages:886–887
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.20220821

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December 2022

Neurofeedback for ADHD: Time to Call It Quits?

James J. McGough, M.D., M.S.

Pages:888–889
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.20220861

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December 2022

An Innovative Approach to Extending the Antidepressant Effects of Intravenous Ketamine in Major Depression

Alan F. Schatzberg, M.D.

Pages:890–891
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.20220812

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Clinical Case Conference

December 2022

A Case of Prolonged Mania, Psychosis, and Severe Depression After Psilocybin Use: Implications of Increased Psychedelic Drug Availability

Gregory Barber, M.D.,
Charles B. Nemeroff, M.D., Ph.D.,
Steven Siegel, M.D., Ph.D.

Pages:892–896
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.22010073

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Reviews and Overviews

December 2022

Technology and Mental Health: State of the Art for Assessment and Treatment

Philip D. Harvey, Ph.D.,
Colin A. Depp, Ph.D.,
Albert A. Rizzo, Ph.D.,
Gregory P. Strauss, Ph.D.,
David Spelber, M.D.,
Linda L. Carpenter, M.D.,
Ned H. Kalin, M.D.,
John H. Krystal, M.D.,
William M. McDonald, M.D.,
Charles B. Nemeroff, M.D., Ph.D.,
Carolyn I. Rodriguez, M.D., Ph.D.,
Alik S. Widge, M.D., Ph.D.,
John Torous, M.D.

Pages:897–914
Published Online:6 October 2022

https://doi.org/10.1176/appi.ajp.21121254

Abstract
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CME

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Technology is ubiquitous in society and is now being extensively used in mental health applications. Both assessment and treatment strategies are being developed and deployed at a rapid pace. The authors review the current domains of technology ...

Articles

December 2022

Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial

Glenn-Milo Santos, Ph.D., M.P.H.,
Janet Ikeda, M.A.,
Phillip Coffin, M.D., M.I.A.,
John Walker, N.P.,
Tim Matheson, Ph.D.,
Arsheen Ali, B.A.,
Matthew McLaughlin, A.B.,
Jennifer Jain, Ph.D., M.P.H.,
Justine Arenander, M.S.W.,
Eric Vittinghoff, Ph.D.,
Steven Batki, M.D.

Pages:915–926
Published Online:26 October 2022

https://doi.org/10.1176/appi.ajp.20220335

Abstract
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Objective:The authors sought to determine the efficacy of targeted naltrexone in sexual and gender minority men (SGM) who binge drink and have mild to moderate alcohol use disorder.Methods:In a double-blind placebo-controlled trial, a total of 120 SGM who ...

December 2022

Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial

Carlos M. Grilo, Ph.D.,
Janet A. Lydecker, Ph.D.,
Sarah K. Fineberg, M.D., Ph.D.,
Jorge O. Moreno, M.D.,
Valentina Ivezaj, Ph.D.,
Ralitza Gueorguieva, Ph.D.

Pages:927–937
Published Online:26 October 2022

https://doi.org/10.1176/appi.ajp.20220267

Abstract
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Objective:Binge-eating disorder, the most prevalent eating disorder, is a serious public health problem associated with obesity, psychiatric and medical comorbidities, and functional impairments. Binge-eating disorder remains underrecognized and ...

December 2022

Effectiveness of Antipsychotic Use for Reducing Risk of Work Disability: Results From a Within-Subject Analysis of a Swedish National Cohort of 21,551 Patients With First-Episode Nonaffective Psychosis

Marco Solmi, M.D., Ph.D.,
Heidi Taipale, Ph.D.,
Minna Holm, Ph.D.,
Antti Tanskanen, Ph.D.,
Ellenor Mittendorfer-Rutz, Ph.D.,
Christoph U. Correll, M.D., Ph.D.,
Jari Tiihonen, M.D., Ph.D.

Pages:938–946
Published Online:6 October 2022

https://doi.org/10.1176/appi.ajp.21121189

Abstract
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Objective:The authors sought to determine whether antipsychotic use, compared with nonuse, is associated with lower work disability in first-episode nonaffective psychosis, and if so, for how long.Methods:A within-subject design was used to study the risk ...

December 2022

Double-Blind, Sham-Controlled Randomized Trial Testing the Efficacy of fMRI Neurofeedback on Clinical and Cognitive Measures in Children With ADHD

Sheut-Ling Lam, Ph.D.,
Marion Criaud, Ph.D.,
Steve Lukito, Ph.D.,
Samuel J. Westwood, Ph.D.,
Deborah Agbedjro, Ph.D.,
Olivia S. Kowalczyk, Ph.D.,
Sarah Curran, M.D., Ph.D.,
Nadia Barret, M.D.,
Chris Abbott, M.D.,
Holan Liang, M.A, M.D.,
Emily Simonoff, M.D.,
Gareth J. Barker, Ph.D.,
Vincent Giampietro, Ph.D.,
Katya Rubia, Ph.D.

Pages:947–958
Published Online:9 November 2022

https://doi.org/10.1176/appi.ajp.21100999

Abstract
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Objective:Functional MRI neurofeedback (fMRI-NF) could potentially be a novel, safe nonpharmacological treatment for attention deficit hyperactivity disorder (ADHD). A proof-of-concept randomized controlled trial of fMRI-NF of the right inferior frontal ...

December 2022

A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical Trial

Rebecca B. Price, Ph.D.,
Crystal Spotts, M.Ed.,
Benjamin Panny, B.S.,
Angela Griffo, B.S.,
Michelle Degutis, M.S.,
Nicolas Cruz, M.Ed.,
Elizabeth Bell, B.S.,
Kevin Do-Nguyen, B.S.,
Meredith L. Wallace, Ph.D.,
Sanjay J. Mathew, M.D.,
Robert H. Howland, M.D.

Pages:959–968
Published Online:21 September 2022

https://doi.org/10.1176/appi.ajp.20220216

Abstract
Full text
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CME

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Objective:Intravenous ketamine, which displays rapid antidepressant properties, is posited to reverse depression by rapidly enhancing neuroplasticity. The authors tested whether an automated, computer-based approach could efficiently leverage enhanced ...

Residents’ Journal

December 2022

Highlights From the Residents’ Journal: September 2022

Page:969
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.22179011

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Appreciation

December 2022

Reviewers for The American Journal of Psychiatry

Pages:970–973
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.22179010

First Page
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Other Items of Interest

December 2022

Page:973
Published Online:1 December 2022

https://doi.org/10.1176/appi.ajp.973correction

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