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American Journal of Psychiatry

Volume 168, Issue 3

March 2011

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In This Issue

March 2011

Page:A36
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2011.168.3.a36

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Editorials

March 2011

Can Epidemiology Translate Into Understanding Major Depression With Borderline Personality Disorder?

Myrna M. Weissman, Ph.D.

Pages:231–233
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10121737

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March 2011

Betting on Biomarkers

Roy H. Perlis, M.D., M.SC.

Pages:234–236
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10121738

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March 2011

Imaging Emotion in Schizophrenia: Not Finding Feelings in All the Right Places

James M. Gold, Ph.D.

Pages:237–239
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10111653

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March 2011

Medication Adherence and Relapse in Recent-Onset Psychosis

Delbert G. Robinson, M.D.

Pages:240–242
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10121736

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Introspection

March 2011

Lessons From Jimmy

Elaine Weiner, M.D.

Pages:243–244
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101562

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Clinical Case Conference

March 2011

Anti-NMDA Receptor Encephalitis: Diagnosis, Psychiatric Presentation, and Treatment

Meredith R. Chapman, M.D., and
Holly E. Vause, D.N.P., P.M.H.N.P.-B.C.

Pages:245–251
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10020181

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Images in Psychiatry

March 2011

Albert Deutsch, 1905-1961

Kenneth J. Weiss, M.D.

Page:252
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101491

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Reviews and Overviews

March 2011

After GWAS: Searching for Genetic Risk for Schizophrenia and Bipolar Disorder

Elliot S. Gershon, M.D.,
Ney Alliey-Rodriguez, M.D., and
Chunyu Liu, Ph.D.

Pages:253–256
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10091340

Abstract
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Ten years ago it was widely expected that the genetic basis of common disease would be resolved by genome-wide association studies (GWAS), large-scale studies in which the entire genome is covered by genetic markers. However, the bulk of heritable ...

Articles

March 2011

Relationship of Personality Disorders to the Course of Major Depressive Disorder in a Nationally Representative Sample

Andrew E. Skodol, M.D.,
Carlos M. Grilo, Ph.D.,
Katherine M. Keyes, M.P.H., Ph.D.,
Timothy Geier, B.A.,
Bridget F. Grant, Ph.D., and
Deborah S. Hasin, Ph.D.

Pages:257–264
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10050695

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Objective:The purpose of this study was to examine the effects of specific personality disorder comorbidity on the course of major depressive disorder in a nationally representative sample. Method:Data were drawn from 1,996 participants in a national ...

March 2011

Pharmacogenetic Approach at the Serotonin Transporter Gene as a Method of Reducing the Severity of Alcohol Drinking

Bankole A. Johnson, D.Sc., M.D.,
Nassima Ait-Daoud, M.D.,
Chamindi Seneviratne, M.D.,
John D. Roache, Ph.D.,
Martin A. Javors, Ph.D.,
Xin-Qun Wang, M.S.,
Lei Liu, Ph.D.,
J. Kim Penberthy, Ph.D.,
Carlo C. DiClemente, Ph.D., and
Ming D. Li, Ph.D.

Pages:265–275
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10050755

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Objective:Severe drinking can cause serious morbidity and death. Because the serotonin transporter (5-HTT) is an important regulator of neuronal 5-HT function, allelic differences at that gene may modulate the severity of alcohol consumption and predict ...

March 2011

Prefrontal Cortical Deficits and Impaired Cognition-Emotion Interactions in Schizophrenia

Stefan Ursu, M.D., Ph.D.,
Ann M. Kring, Ph.D.,
Marja Germans Gard, Ph.D.,
Michael J. Minzenberg, M.D.,
Jong H. Yoon, M.D.,
J. Daniel Ragland, Ph.D.,
Marjorie Solomon, Ph.D., and
Cameron S. Carter, M.D.

Pages:276–285
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.09081215

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Objective:Despite schizophrenia patients' reports of diminished experience of emotion in interviews and self-report measures, their emotional experience in the presence of emotional stimuli and in daily life (“in the moment”) appears largely intact. To ...

March 2011

Risperidone Nonadherence and Return of Positive Symptoms in the Early Course of Schizophrenia

Kenneth L. Subotnik, Ph.D.,
Keith H. Nuechterlein, Ph.D.,
Joseph Ventura, Ph.D.,
Michael J. Gitlin, M.D.,
Stephen Marder, M.D.,
Jim Mintz, Ph.D.,
Gerhard S. Hellemann, Ph.D.,
Leslie A. Thornton, Ph.D., and
Indira R. Singh, B.S.

Pages:286–292
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.09010087

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Objective:This study examined the effect of medication nonadherence on the return of positive symptoms among recent-onset schizophrenia patients. Method:Three sets of operational criteria for medication nonadherence with differing levels of severity were ...

March 2011

Abnormal Modulation of Amygdala Activity in Schizophrenia in Response to Direct- and Averted-Gaze Threat-Related Facial Expressions

Amy E. Pinkham, Ph.D.,
James Loughead, Ph.D.,
Kosha Ruparel, M.S.E.,
Eve Overton, B.A.,
Raquel E. Gur, M.D., Ph.D., and
Ruben C. Gur, Ph.D

Pages:293–301
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10060832

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Objective:Reduced amygdala activation in individuals with schizophrenia is thought to contribute to impairments in emotion recognition and social functioning. Recent work, however, suggests that amygdala abnormalities in schizophrenia are more nuanced ...

March 2011

Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications

Douglas F. Levinson, M.D.,
Jubao Duan, Ph.D.,
Sang Oh, M.Sc.,
Kai Wang, Ph.D.,
Alan R. Sanders, M.D.,
Jianxin Shi, Ph.D.,
Nancy Zhang, Ph.D.,
Bryan J. Mowry, M.D., F.R.A.N.Z.C.P.,
Ann Olincy, M.D.,
Farooq Amin, M.D.,
C. Robert Cloninger, M.D.,
Jeremy M. Silverman, M.D.,
Nancy G. Buccola, A.P.R.N., B.C.,
William F. Byerley, M.D.,
Donald W. Black, M.D.,
Kenneth S. Kendler, M.D.,
Robert Freedman, M.D.,
Frank Dudbridge, Ph.D.,
Itsik Pe'er, Ph.D.,
Hakon Hakonarson, M.D., Ph.D.,
Sarah E. Bergen, Ph.D.,
Ayman H. Fanous, M.D.,
Peter A. Holmans, Ph.D., and
Pablo V. Gejman, M.D.

Pages:302–316
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10060876

Abstract
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Objective:To evaluate previously reported associations of copy number variants (CNVs) with schizophrenia and to identify additional associations, the authors analyzed CNVs in the Molecular Genetics of Schizophrenia study (MGS) and additional available ...

March 2011

Overactive Error-Related Brain Activity as a Candidate Endophenotype for Obsessive-Compulsive Disorder: Evidence From Unaffected First-Degree Relatives

Anja Riesel, Dipl.-Psych.,
Tanja Endrass, Ph.D.,
Christian Kaufmann, Dipl.-Psych., and
Norbert Kathmann, Ph.D.

Pages:317–324
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10030416

Abstract
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Objective:Hyperactivity in frontal-striatal circuits is assumed to be involved in the pathophysiology of obsessive-compulsive disorder (OCD). In line with that, electrocortical correlates of overactive performance monitoring have been found to be ...

Letters to the Editor

March 2011

The Association of Stigma With Violence

E. Fuller Torrey, M.D.

Page:325
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2011.10121710

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March 2011

Response to Torrey Letter

Bernice A. Pescosolido, Ph.D.

Pages:325–326
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2011.10121710r

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March 2011

Current Smoking, Hypoxia, and Suicide

Henri-Jean Aubin,

Ivan Berlin, and

Michel Reynaud

Pages:326–327
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101501

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March 2011

Meta-Cognitive Therapy Without Metacognition: A Case of ADHD

Adrian Wells, Ph.D., and
Peter Fisher, Ph.D.

Page:327
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101467

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March 2011

Response to Wells and Fisher Letter

Mary V. Solanto, Ph.D.,
Jeanette Wasserstein, Ph.D., and
David J. Marks, Ph.D.

Pages:327–328
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101467r

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March 2011

Response to Aubin et al. Letter

Namkug Kim, Ph.D.,
Deborah A. Yurgelun-Todd, Ph.D., and
Perry F. Renshaw, M.D., Ph.D.

Page:327
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.1010150r

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March 2011

Study Limitations in Report of Suicidal Behavior Among Women With Co-occurring PTSD and Borderline Personality Disorder

Josh Nepon, M.D.,
Jina Pagura, M.A., and
Jitender Sareen, M.D.

Page:328
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101551

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March 2011

Response to Nepon et al. Letter

Melanie S. Harned, Ph.D.,

Shireen L. Rizvi, Ph.D., and

Marsha M. Linehan, Ph.D.

Pages:328–329
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10101551r

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March 2011

Self-Reported Incidences of Moving Vehicle Collisions and Citations Among Drivers With ADHD: A Cross-Sectional Survey Across the Lifespan

Daniel J. Cox, Ph.D.,

Brian S. Cox, B.S., and
Jennifer Cox, M.S.

Pages:329–330
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10091355

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March 2011

Oxybutynin for Antidepressant-Induced Hyperhidrosis

Koen P. Grootens, M.D., Ph.D.

Pages:330–331
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10091348

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Book Forum

March 2011

The Panic Virus: A True Story of Medicine, Science, and Fear

Roy R. Grinker, PH.D.

Pages:332–333
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2011.11010045

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March 2011

Cold War in Psychiatry: Human Factors, Secret Actors

Paul S. Appelbaum, M.D.

Pages:333–334
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10111651

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March 2011

Antipsychotic Trials in Schizophrenia: The CATIE Project

Dost Ongur, M.D., PH.D.

Page:334
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10091362

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March 2011

Schizotypy and Schizophrenia: The View from Experimental Psychopathology

Tonya White, M.D., PH.D.

Pages:334–335
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2010.10111629

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Books Received

March 2011

Page:336
Published Online:1 March 2011

https://doi.org/10.1176/appi.ajp.2011.168.3.336

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