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References

  • 1 Kessler RC, Sonnega A, Bromet E, et al.: Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 1995; 52:1048–1060 Crossref, MedlineGoogle Scholar
  • 2 Hoge CW, Castro CA, Messer SC, et al.: Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med 2004; 351:13–22 Crossref, MedlineGoogle Scholar
  • 3 American Psychiatric Association: Diagnostic and Statistic Manual for Mental Disorders, 5th ed. Washington, DC, APA, 2013 CrossrefGoogle Scholar
  • 4 Hamner MB: Psychotic features and combat-associated PTSD. Depress Anxiety 1997; 5:34–38 Crossref, MedlineGoogle Scholar
  • 5 David D, Kutcher GS, Jackson EI, et al.: Psychotic symptoms in combat-related posttraumatic stress disorder. J Clin Psychiatry 1999; 60:29–32 Crossref, MedlineGoogle Scholar
  • 6 Hamner MB, Frueh BC, Ulmer HG, et al.: Psychotic features in chronic posttraumatic stress disorder and schizophrenia: comparative severity. J Nerv Ment Dis 2000; 188:217–221 Crossref, MedlineGoogle Scholar
  • 7 Foa EB, Keane TM, Friedman MJ, et al.: Effective Treatments for PTSD: Practice Guidelines From the International Society for Traumatic Stress Studies. New York, Guilford Press, 2008 Google Scholar
  • 8 van der Kolk BA, Dreyfuss D, Michaels M, et al.: Fluoxetine in posttraumatic stress disorder. J Clin Psychiatry 1994; 55:517–522 MedlineGoogle Scholar
  • 9 Hertzberg MA, Feldman ME, Beckham JC, et al.: Lack of efficacy for fluoxetine in PTSD: a placebo controlled trial in combat veterans. Ann Clin Psychiatry 2000; 12:101–105 Crossref, MedlineGoogle Scholar
  • 10 Zohar J, Amital D, Miodownik C, et al.: Double-blind placebo-controlled pilot study of sertraline in military veterans with posttraumatic stress disorder. J Clin Psychopharmacol 2002; 22:190–195 Crossref, MedlineGoogle Scholar
  • 11 Cañive JM, Clark RD, Calais LA, et al.: Bupropion treatment in veterans with posttraumatic stress disorder: an open study. J Clin Psychopharmacol 1998; 18:379–383 Crossref, MedlineGoogle Scholar
  • 12 Hamner MB, Faldowski RA, Ulmer HG, et al.: Adjunctive risperidone treatment in post-traumatic stress disorder: a preliminary controlled trial of effects on comorbid psychotic symptoms. Int Clin Psychopharmacol 2003; 18:1–8 Crossref, MedlineGoogle Scholar
  • 13 Hamner MB, Robert S, Frueh BC: Treatment-resistant posttraumatic stress disorder: strategies for intervention. CNS Spectr 2004; 9:740–752 Crossref, MedlineGoogle Scholar
  • 14 Villarreal G, Calais LA, Cañive JM, et al.: Prospective study to evaluate the efficacy of aripiprazole as a monotherapy in patients with severe chronic posttraumatic stress disorder: an open trial. Psychopharmacol Bull 2007; 40:6–18 MedlineGoogle Scholar
  • 15 Stein MB, Kline NA, Matloff JL: Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study. Am J Psychiatry 2002; 159:1777–1779 LinkGoogle Scholar
  • 16 Carey P, Suliman S, Ganesan K, et al.: Olanzapine monotherapy in posttraumatic stress disorder: efficacy in a randomized, double-blind, placebo-controlled study. Hum Psychopharmacol 2012; 27:386–391 Crossref, MedlineGoogle Scholar
  • 17 Ahearn EP, Juergens T, Cordes T, et al.: A review of atypical antipsychotic medications for posttraumatic stress disorder. Int Clin Psychopharmacol 2011; 26:193–200 MedlineGoogle Scholar
  • 18 Krystal JH, Rosenheck RA, Cramer JA, et al.: Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial. JAMA 2011; 306:493–502 Crossref, MedlineGoogle Scholar
  • 19 Richelson E, Souder T: Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci 2000; 68:29–39 Crossref, MedlineGoogle Scholar
  • 20 Nikisch G, Baumann P, Liu T, et al.: Quetiapine affects neuropeptide Y and corticotropin-releasing hormone in cerebrospinal fluid from schizophrenia patients: relationship to depression and anxiety symptoms and to treatment response. Int J Neuropsychopharmacol 2012; 15:1051–1061 Crossref, MedlineGoogle Scholar
  • 21 López-Muñoz F, Alamo C: Active metabolites as antidepressant drugs: the role of norquetiapine in the mechanism of action of quetiapine in the treatment of mood disorders. Front Psychiatry 2013; 4:102 Crossref, MedlineGoogle Scholar
  • 22 Hamner MB, Deitsch SE, Brodrick PS, et al.: Quetiapine treatment in patients with posttraumatic stress disorder: an open trial of adjunctive therapy. J Clin Psychopharmacol 2003; 23:15–20 Crossref, MedlineGoogle Scholar
  • 23 Robert S, Hamner MB, Kose S, et al.: Quetiapine improves sleep disturbances in combat veterans with PTSD: sleep data from a prospective, open-label study. J Clin Psychopharmacol 2005; 25:387–388 Crossref, MedlineGoogle Scholar
  • 24 Byers MG, Allison KM, Wendel CS, et al.: Prazosin versus quetiapine for nighttime posttraumatic stress disorder symptoms in veterans: an assessment of long-term comparative effectiveness and safety. J Clin Psychopharmacol 2010; 30:225–229 Crossref, MedlineGoogle Scholar
  • 25 Department of Veterans Affairs and Department of Defense: VA/DoD Clinical Practice Guideline for the Management of Post-Traumatic Stress, 2010 ( http://www.healthquality.va.gov/guidelines/MH/ptsd/cpgPTSDFULL201011612c.pdf) Google Scholar
  • 26 Blake DD, Weathers FW, Nagy LM, et al.: The development of a Clinician-Administered PTSD Scale. J Trauma Stress 1995; 8:75–90 Crossref, MedlineGoogle Scholar
  • 27 First MB, Spitzer RL, Gibbon M, et al.: Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. (SCID-I/P). New York, New York State Psychiatric Institute, Biometrics Research, 2002 Google Scholar
  • 28 Bauer MS, Lee A, Li M, et al.: Off-label use of second generation antipsychotics for post-traumatic stress disorder in the Department of Veterans Affairs: time trends and sociodemographic, comorbidity, and regional correlates. Pharmacoepidemiol Drug Saf 2014; 23:77–86 Crossref, MedlineGoogle Scholar
  • 29 Hermes E, Sernyak M, Rosenheck R: The use of second generation antipsychotics for post-traumatic stress disorder in a US Veterans Health Administration Medical Center. Epidemiol Psychiatr Sci 2014; 23:281–288 Crossref, MedlineGoogle Scholar
  • 30 Thase ME: Quetiapine monotherapy for bipolar depression. Neuropsychiatr Dis Treat 2008; 4:11–21 MedlineGoogle Scholar
  • 31 Mohamed S, Rosenheck RA: Pharmacotherapy of PTSD in the U.S. Department of Veterans Affairs: diagnostic- and symptom-guided drug selection. J Clin Psychiatry 2008; 69:959–965 Crossref, MedlineGoogle Scholar
  • 32 Raskind MA, Peterson K, Williams T, et al.: A trial of prazosin for combat trauma PTSD with nightmares in active-duty soldiers returned from Iraq and Afghanistan. Am J Psychiatry 2013; 170:1003–1010 LinkGoogle Scholar
  • 33 Hamner MB, Arvanitis LA, Miller BG, et al.: Plasma prolactin in schizophrenia subjects treated with Seroquel (ICI 204,636). Psychopharmacol Bull 1996; 32:107–110 MedlineGoogle Scholar
  • 34 Benedek DM, Friedman MJ, Zatzick D, Ursano RJ: Guideline Watch (March 2009): Practice Guideline for the Treatment of Patients With Acute Stress Disorder and Posttraumatic Stress Disorder. ( http://psychiatryonline.org/pb/assets/raw/sitewide/practice_guidelines/guidelines/acutestressdisorderptsd-watch.pdf) Google Scholar
  • 35 Newcomer JW: Antipsychotic medications: metabolic and cardiovascular risk. J Clin Psychiatry 2007; 68(suppl 4):8–13 Crossref, MedlineGoogle Scholar