AN EXAMINATION OF THE CLINICO-PATHOLOGICAL EVIDENCE OFFERED FOR THE CONCEPT OF DEMENTIA PRÆCOX AS A SPECIFIC DISEASE ENTITY
Abstract
An examination of the clinico-pathological evidence offered for the concept of dementia præcox as a specific disease entity presents the following conclusions:
1. There are many contradictory opinions expressed on the topic of a uniform anatomical basis to this disorder. There has been no satisfactory correlation made between the so-called classical groups of dementia præcox and specific anatomical findings.
2. The same histopathological findings which are reported as being specific for these groups are also reported as being present in a variety of organic and toxic conditions.
3. There is no uniformity to be found in the various clinical contributions as to what constitutes a dementia præcox reaction.
4. The attempt to group these heterogeneous findings into a specific disease entity comparable to that of general paralysis has proven to be progressively less productive of constructive formulations over a period of 50 years of intensive research.
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