The role of gender in studies of ventricle enlargement in schizophrenia: a predominantly male effect
Abstract
Two previously reported neuroimaging studies from the authors' laboratory demonstrated larger lateral ventricles in schizophrenic patients than in normal control subjects. This diagnostic effect was accounted for almost entirely by the male subjects. In this report the role of gender is further explored through reexamining these data sets and those of two earlier studies. Although Gender by Diagnosis effects were not demonstrated, in three of the four studies male schizophrenic subjects had significantly larger ventricles than their control counterparts; there were no differences among the female subjects. One study suggested the opposite effect, but this may be attributable to a non-representative control group.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).