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Phenomenology and family history of affective disorder in Cushing's disease

Published Online:https://doi.org/10.1176/ajp.144.7.951

Of 16 patients with Cushing's disease, 13 (81%) had lifetime diagnoses of major affective disorder according to DSM-III criteria. However, the rate of familial major affective disorder among these patients was significantly lower than that found among patients with major depression.

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