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Clonidine in neuroleptic-induced akathisia

Published Online:https://doi.org/10.1176/ajp.144.2.235

Six hospitalized patients with neuroleptic-induced akathisia were treated with clonidine under single-blind conditions. Akathisia and anxiety at maximum clonidine dose were significantly lower than at baseline, although it was difficult to differentiate specific therapeutic effects from sedation.

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