Biochemical RBC abnormalities in drug-free and lithium-treated manic patients
Abstract
RBCs from two lithium-free manic patients displayed lower choline transport and higher choline concentrations and methionine S- adenosyltransferase activity than those of controls. Lithium therapy decreased RBC methionine S-adenosyltransferase activity to normal, decreased choline transport further, and increased choline concentrations further.
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