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Plasma GABA levels in chronic alcoholics

Published Online:https://doi.org/10.1176/ajp.142.10.1204

Ethanol intoxication has been noted to cause marked changes in brain and CSF levels of gamma-aminobutyric acid (GABA). Using plasma GABA levels to assess brain GABA activity, the authors found that 85 chronic alcoholics had significantly lower levels than control subjects.

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