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Treatment of lithium tremor with metoprolol

Published Online:https://doi.org/10.1176/ajp.140.5.593

Two patients with bipolar affective disorder and a history of bronchospastic phenomena experienced tremor during lithium carbonate therapy. In both, metoprolol produced objective and subjective improvement of the tremor without producing bronchospasm. Objective improvement of tremor after use of metoprolol was documented by accelerometry. The authors discuss the implications of these findings.

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