CSF copper in schizophrenia
Abstract
The authors measured copper levels in the cerebrospinal fluid of 8 schizophrenic subjects and 6 controls. The schizophrenic subjects had significantly lower CSF copper values than the controls, which is consistent with the hypothesis that there is reduced central activity of copper-dependent enzymes in schizophrenia. These enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase, are involved in the synthesis and catabolism of dopamine.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).
