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Choline chloride treatment of memory deficits in the elderly

Published Online:https://doi.org/10.1176/ajp.136.10.1275

Eight elderly patients with mild memory impairment were given choline chloride, a drug that increases brain acetylcholine concentrations. After 16 g/day of choline for 7 days, average memory performance was not different from performance during pre- and postcholine placebo treatment, although the patient with the poorest baseline performance improved considerably on choline.

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