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Prediction of individual dosage of nortriptyline

Published Online:https://doi.org/10.1176/ajp.135.3.333

The authors describe a technique that enables a physician to determine individual patient dosage requirements for nortriptyline from a single 24-hour blood sample. Because the technique reveals immediately those patients at the extremes of dosage ranges, toxicity and the need for time-consuming titration of the dosage regimen can be avoided.

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