Amitriptyline in Anxious-Depressed Outpatients: A Controlled Study
Abstract
In a four-week study of 08 volunteer subjects with mixed symptoms of anxiety and depression, amitriptyline produced significantly more improvement than placebo. Significant differences were noted between the amitriptyline and placebo treatment groups at two weeks in relief of somatic and anxiety symptoms and at four weeks in relief of depressive symptoms. The marked sensitivity of the volunteers to certain amitriptyline-induced side effects appeared to be related to their relatively high level of education, employment, and anxiety. Comparison data indicated that the results obtained with volunteers are relevant to outpatients treated in general practice.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).