Lithium and Thyroid Function in Manic-Depressive Psychosis
Abstract
The authors report a possible long-termn side effect of lithium treatment in cases of manic-depressive disease. They examined 19 manic-depressive patients who had been on long-term lithium carbonate therapy and found that six had goiters and four others had evidence of thyroid pathology. Related studies and findings are reported, and possible mechanisms underlying the high incidence of thyroid pathology are discussed.
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