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VISUAL HALLUCINATIONS WITH IMIPRAMINE

Published Online:https://doi.org/10.1176/ajp.121.9.911

The occasional occurrence of imipramine-induced visual hallucinations resembling those produced by hallucinogenic agents is documented. The phenomenon is dosage dependent and easily managed by reduction of dosage level when recognized. Delirious confusion is not a necessary part of this syndrome. This phenomenon's relationships to age, diagnosis, and psychopathological features are discussed and contrasted with visual hallucinations of schizophrenia. The possibility of a common organic CNS predisposition to depersonalization, derealization, and visual hallucinosis is indicated.

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