The American Psychiatric Association (APA) has updated its Privacy Policy and Terms of Use, including with new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences.

Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.

×
Published Online:https://doi.org/10.1176/ajp.109.8.621

We have studied fatigue curves in 65 normal subjects, 50 patients with myasthenia gravis, 25 patients with Parkinson's disease, 50 patients with miscellaneous neurological conditions such as poliomyelitis, arthritis, and dystrophy, and 40 patients who did not have any structural disease of their muscular or nervous systems but whose complaint was chronic fatigue and who had symptoms of nervousness, indicating that their fatigue was of psychogenic origin.

The site of pathology of the fatigue in the neurological cases mentioned may be in the muscle, the end-plate, or in the peripheral nerve. However, the source of the fatigue complaint in patients with chronic fatigue of nonneurological nature and not due to medical diseases lies in the brain. Treatment of this type of disease must be directed toward determining the psychological causes of the fatigue and correcting them. The prescribing of muscular rest with the idea that the muscles are at fault is a waste of time.

Access content

To read the fulltext, please use one of the options below to sign in or purchase access.