Complementary Features of Attention Bias Modification Therapy and Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders
Abstract
Objective:
Method:
Results:
Conclusions:
Method
Participants
Characteristic or Measure | Anxiety Group (N=54) | Healthy Comparison Group (N=51) | ||
---|---|---|---|---|
N | % | N | % | |
Female | 32 | 59.3 | 23 | 45.1 |
Mean | SD | Mean | SD | |
Age (years) | 12.08 | 2.80 | 12.86 | 1.94 |
IQ | 112.78 | 15.55 | 113.18 | 11.58 |
Baseline SCARED total scorea | 29.40 | 9.59 | 5.44 | 4.68 |
Attention Bias Assessment
Treatments
Clinical Treatment Data Analysis
Imaging Data Acquisition and Analysis
fMRI acquisition parameters.
fMRI preprocessing.
fMRI data analysis.
Pretreatment amygdala connectivity:
Amygdala connectivity and treatment response:
Results
Clinical Effects of CBT and ABMT
Characteristic or Measure | Active ABMT Group (N=43) | Placebo ABMT Group (N=42) | ||
---|---|---|---|---|
N | % | N | % | |
Female | 26 | 60.5 | 24 | 57.1 |
Mean | SD | Mean | SD | |
Age (years) | 11.62 | 2.78 | 11.79 | 2.73 |
IQ | 110.42 | 14.66 | 114.00 | 15.50 |
PARS rating | ||||
Pretreatment assessment | 17.03 | 2.56 | 16.84 | 3.03 |
Midtreatment assessment | 15.26 | 3.86 | 15.38 | 2.85 |
Posttreatment assessmentb | 11.97 | 4.69 | 13.67 | 3.25 |
CGI-I | ||||
Midtreatment assessment | 3.86 | 0.80 | 4.23 | 0.69 |
Posttreatment assessment | 3.35 | 0.88 | 3.29 | 0.97 |
Pretreatment Amygdala Connectivity
Amygdala Connectivity and Overall Treatment Response
Amygdala Connectivity and ABMT-Specific Response
Discussion
ABMT Augmentation of Clinical Response
Amygdala-Based Functional Connectivity and Anxiety Disorders
Amygdala-Based Connectivity and Treatment Outcome
Limitations and Conclusions
Footnote
Supplementary Material
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References
Information & Authors
Information
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Keywords
Authors
Competing Interests
Funding Information
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Metrics
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