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Ratio of serum prolactin to haloperidol and early clinical outcome in acute psychosis

Published Online:https://doi.org/10.1176/ajp.141.10.1281

The ratio of the increase in serum prolactin concentration to steady- state haloperidol concentration in acutely psychotic women correlated with early clinical improvement. Correction of prolactin response for neuroleptic concentration may provide a better clinical predictor than either measure alone.

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