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A high-dose, double-blind study of ceruletide in the treatment of schizophrenia

Published Online:https://doi.org/10.1176/ajp.142.12.1482

Ceruletide, a cholecystokinin analogue, has been reported to interact with dopamine in the CNS and to benefit schizophrenic individuals. The authors, using a double-blind design, a higher total dose, and a larger sample size than previous studies, found no evidence of benefit.

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