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Review of the Evidence and Qualifications Regarding the Effects of Hallucinogenic Drugs on Chromosomes and Embryos

Published Online:https://doi.org/10.1176/ajp.126.2.251

Laboratory studies of the effects of hallucinogenic drugs on chromosomes and developing embryos are reviewed. The author concludes that at present there is no adequate evidence that these drugs cause chromosomal damage in vivo or adversely affect progeny as a result of chromosomal changes. However, these drugs when taken early (but not late) in pregnancy appear to have a teratogenic effect.

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