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Published Online:https://doi.org/10.1176/ajp.126.2.149

A considerable amount of biological research into schizophrenia, mainly upon blood fluids, is performed throughout the world. The authors report their latest findings on a plasma protein factor and relate these findings to other domestic research and to recent research in other nations, particularly the Soviet Union. They hypothesize that a malcontrolled blood protein contributes to the genesis of schizophrenia by selectively altering neuronal permeability to precursors of important neurotransmitters; if this occurs, it would disrupt information processing in the brain.

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