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The differential effects of chlordiazepoxide and oxazepam on hostility in a small group setting

Published Online:https://doi.org/10.1176/ajp.132.8.861

The authors compared the effects of chlordiazepoxide, oxazepam, and placebo on hostility, as an inner motivational or arousal state, in moderately and highly anxious male research volunteers. The data again supported the hypothesis that clordiazepoxide-induced increases in motivational hostility are more frequent and intense than those associated with placebo and oxazepum. The data also suggest that oxazepam may be a more specific "hostility tranquilizer" than other benzodiazepines.

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