Alterations in Cell Membrane Activity in Depression
Abstract
Findings from a series of related experiments led to a working hypothesis suggesting that there may be an abnormality in aspects of cell membrane properties that normally regulate the movement of electrolytes across the plasma membrane in a subgroup of depressed patients. These patients appear to be responsive to lithium, and there is evidence that the postulated abnormality may be genetically determined. The authors outline the potential usefulness of the erythrocyte as a model for studying electrolyte transport in neurons.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).
