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American Journal of Psychiatry

Volume 177, Issue 4

April 2020
Cover: This issue of the Journal, which focuses on psychotic disorders with a special emphasis on early symptoms as they relate to risk, has as its centerpiece a thought-provoking overview by Dr. René S. Kahn that emphasizes the importance of cognitive decline prior to a first psychotic episode as being highly relevant to the pathophysiology of schizophrenia. The FA change image depicts the connectome in adolescents and the relationship to decreasing (left) and increasing (right) IQ in teenagers. Image courtesy of Dr. Kahn and Drs. Hilleke Hulshoff Pol and Dorret I. Boomsma.
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Editor’s Note
April 2020
Psychotic Experiences, Cognitive Decline, and Genetic Vulnerabilities in Relation to Developing Psychotic Disorders
  • Pages:279–281
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2020.20020162

Editorials
April 2020
Genetically, Developmentally, and Clinically Distinct Cognitive Subtypes in Schizophrenia: A Tale of Three Trajectories
  • Pages:282–284
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2020.20020132

April 2020
We Need to Talk About Prevention
  • Pages:285–287
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2020.20020155

April 2020
Does Early Intervention Improve the Long-Term Course of Schizophrenia?
  • Pages:288–290
  • Published Online:4 March 2020

https://doi.org/10.1176/appi.ajp.2020.20020111

Reviews and Overviews
April 2020
On the Origins of Schizophrenia
  • Pages:291–297
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2020.20020147

Articles
Video
April 2020
Distinct Polygenic Score Profiles in Schizophrenia Subgroups With Different Trajectories of Cognitive Development
  • Pages:298–307
  • Published Online:16 December 2019

https://doi.org/10.1176/appi.ajp.2019.19050527

Preview Abstract
CMEAudio
April 2020
A Population-Based Cohort Study Examining the Incidence and Impact of Psychotic Experiences From Childhood to Adulthood, and Prediction of Psychotic Disorder
  • Pages:308–317
  • Published Online:7 January 2020

https://doi.org/10.1176/appi.ajp.2019.19060654

Preview Abstract
April 2020
Mental Health Service Use and Psychopharmacological Treatment Following Psychotic Experiences in Preadolescence
  • Pages:318–326
  • Published Online:26 February 2020

https://doi.org/10.1176/appi.ajp.2019.19070724

Preview Abstract
CMEVideo
April 2020
Lead-Time Bias Confounds Association Between Duration of Untreated Psychosis and Illness Course in Schizophrenia
  • Pages:327–334
  • Published Online:12 February 2020

https://doi.org/10.1176/appi.ajp.2019.19030324

Preview Abstract
April 2020
Infections as a Risk Factor for and Prognostic Factor After Substance-Induced Psychoses
  • Pages:335–341
  • Published Online:12 February 2020

https://doi.org/10.1176/appi.ajp.2019.19101047

Preview Abstract
CMEAudio
April 2020
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia
  • Pages:342–353
  • Published Online:16 December 2019

https://doi.org/10.1176/appi.ajp.2019.19010034

Preview Abstract
Letters to the Editor
April 2020
Failing to Gain: Another Explanation of Cognitive Change in Schizophrenia and Other Psychoses in the Decade Following the First Episode
  • Page:354
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2019.19090972

April 2020
Further Analysis of Cognitive Change in Schizophrenia and Other Psychoses in the Decade Following the First Episode: Response to Panayiotou et al.
  • Pages:354–355
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2019.19090972r

April 2020
Are Visual Memory Deficits in Recent-Onset Psychosis Degenerative?
  • Pages:355–356
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2019.19080845

April 2020
Are Visual Memory Deficits in Recent-Onset Psychosis Degenerative? Response to Smucny et al.
  • Pages:356–357
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2019.19080845r

April 2020
The Ambiguity of Maltreatment
  • Pages:357–358
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2020.20010083

Books Received
April 2020
Books Received
  • Page:359
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.2020.17704

Residents’ Journal
April 2020
Highlights From the Residents’ Journal: March 2020
  • Page:360
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.177401

Disclosure of Editors’ Financial Relationships
April 2020
Disclosure of Editors’ Financial Relationships
  • Page:359
  • Published Online:1 April 2020

https://doi.org/10.1176/appi.ajp.1774359

Issue Highlights