Prefrontal GABA Levels Measured With Magnetic Resonance Spectroscopy in Patients With Psychosis and Unaffected Siblings
References
- 1 : Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia. Trends Neurosci 2012; 35:57–67 Crossref, Medline, Google Scholar
- 2 : Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Mol Psychiatry 2012; 17:887–905 Crossref, Medline, Google Scholar
- 3 : Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Mol Psychiatry 2007; 12:854–869 Crossref, Medline, Google Scholar
- 4 : Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia. Arch Gen Psychiatry 2007; 64:156–167 Crossref, Medline, Google Scholar
- 5 : Abnormal neural oscillations and synchrony in schizophrenia. Nat Rev Neurosci 2010; 11:100–113 Crossref, Medline, Google Scholar
- 6 : [123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia. Psychiatry Res 1999; 91:163–173 Crossref, Medline, Google Scholar
- 7 : Tiagabine increases [11C]flumazenil binding in cortical brain regions in healthy control subjects. Neuropsychopharmacology 2009; 34:624–633 Crossref, Medline, Google Scholar
- 8 : Acute increases in synaptic GABA detectable in the living human brain: a [¹¹C]Ro15-4513 PET study. Neuroimage 2014; 99:158–165 Crossref, Medline, Google Scholar
- 9 : In vivo measurement of GABA transmission in healthy subjects and schizophrenia patients. Am J Psychiatry 2015; 172:1148–1159 Link, Google Scholar
- 10 : GABA concentration in schizophrenia patients and the effects of antipsychotic medication: a proton magnetic resonance spectroscopy study. Schizophr Res 2010; 117:83–91 Crossref, Medline, Google Scholar
- 11 : In vivo measurements of glutamate, GABA, and NAAG in schizophrenia. Schizophr Bull 2013; 39:1096–1104 Crossref, Medline, Google Scholar
- 12 : Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Mol Psychiatry 2015; 20:433–439. Crossref, Medline, Google Scholar
- 13 : GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression. J Neurosci 2010; 30:3777–3781 Crossref, Medline, Google Scholar
- 14 : Perceptual and cognitive effects of antipsychotics in first-episode schizophrenia: the potential impact of GABA concentration in the visual cortex. Prog Neuropsychopharmacol Biol Psychiatry 2013; 47:13–19 Crossref, Medline, Google Scholar
- 15 : GABA and glutamate in schizophrenia: a 7 T ¹H-MRS study. Neuroimage Clin 2014; 6:398–407 Crossref, Medline, Google Scholar
- 16 : Medial frontal GABA is lower in older schizophrenia: a MEGA-PRESS with macromolecule suppression study. Mol Psychiatry (Epub ahead of print, March 31, 2015) Google Scholar
- 17 : Reduction of brain gamma-aminobutyric acid (GABA) concentrations in early-stage schizophrenia patients: 3T proton MRS study. Schizophr Res 2009; 112:192–193 Crossref, Medline, Google Scholar
- 18 : GABA levels in medial prefrontal cortex of patients with schizophrenia: a proton magnetic resonance spectroscopy (1H-MRS) study. Biol Psychiatry 2007; 61:77S Google Scholar
- 19 : Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. Arch Gen Psychiatry 2012; 69:449–459 Crossref, Medline, Google Scholar
- 20 : Elevated gamma-aminobutyric acid levels in chronic schizophrenia. Biol Psychiatry 2010; 68:667–670 Crossref, Medline, Google Scholar
- 21 : No alterations of brain GABA after 6 months of treatment with atypical antipsychotic drugs in early-stage first-episode schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34:1480–1483 Crossref, Medline, Google Scholar
- 22 : Genetic association of ErbB4 and human cortical GABA levels in vivo. J Neurosci 2011; 31:11628–11632 Crossref, Medline, Google Scholar
- 23 : Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT. Neuropsychopharmacology 2010; 35:1708–1717 Crossref, Medline, Google Scholar
- 24 : Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nat Rev Neurosci 2006; 7:818–827 Crossref, Medline, Google Scholar
- 25 : The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13:261–276 Crossref, Medline, Google Scholar
- 26 : Searching for a consensus five-factor model of the Positive and Negative Syndrome Scale for schizophrenia. Schizophr Res 2012; 137:246–250 Crossref, Medline, Google Scholar
- 27 : Reproducibility of prefrontal γ-aminobutyric acid measurements with J-edited spectroscopy. NMR Biomed 2011; 24:1089–1098 Crossref, Medline, Google Scholar
- 28 : Evaluation of anatomic variation in macromolecule contribution to the GABA signal using metabolite nulling and the J-editing technique at 3.0 T. Proc Intl Soc Mag Reson Med 2007; 15:1391 Google Scholar
- 29 : Multimodal image coregistration and partitioning: a unified framework. Neuroimage 1997; 6:209–217 Crossref, Medline, Google Scholar
- 30 : Long-term treatment of rats with haloperidol: lack of an effect on brain N-acetyl aspartate levels. Neuropsychopharmacology 2006; 31:751–756 Crossref, Medline, Google Scholar
- 31 : Chronic haloperidol potentiates stimulated glutamate release in caudate putamen, but not prefrontal cortex. Neuroreport 1995; 6:1795–1798 Crossref, Medline, Google Scholar
- 32 : Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain. Psychopharmacology (Berl) 2013; 230:57–67 Crossref, Medline, Google Scholar
- 33 : Analyzing the effects of psychotropic drugs on metabolite profiles in rat brain using 1H NMR spectroscopy. J Proteome Res 2009; 8:1943–1952 Crossref, Medline, Google Scholar
- 34 : Chronic haloperidol-induced alterations in pallidal GABA and striatal D(1)-mediated dopamine turnover as measured by dual probe microdialysis in rats. Neuroscience 2000; 100:507–514 Crossref, Medline, Google Scholar
- 35 : The consequences of long-term antipsychotic drug administration on basal ganglia neuronal function in laboratory animals. Crit Rev Neurobiol 1994; 8:85–124 Medline, Google Scholar
- 36 : Acute versus chronic haloperidol: relationship between tolerance to catalepsy and striatal and accumbens dopamine, GABA, and acetylcholine release. Brain Res 1994; 634:20–30 Crossref, Medline, Google Scholar
- 37 : Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs. Eur J Neurosci 2003; 18:391–402 Crossref, Medline, Google Scholar
- 38 : Differential effects of long-term treatment with clozapine or haloperidol on GABAA receptor binding and GAD67 expression. Schizophr Res 2004; 66:151–157 Crossref, Medline, Google Scholar
- 39 : Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy. Biol Psychiatry 2005; 57:44–48 Crossref, Medline, Google Scholar
- 40 : Frontal GABA levels change during working memory. PLoS One 2012; 7:e31933 Crossref, Medline, Google Scholar