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Relationship of cognitive factors to CSF corticotropin-releasing hormone in depression

Published Online:https://doi.org/10.1176/ajp.147.3.350

The authors investigated the relationship between items on the Beck Depression Inventory and CSF levels of corticotropin-releasing hormone (CRH) in 17 depressed patients. Linear regression analysis showed that self-accusation, expectation of punishment, and crying accounted for 82% of CRH variance.

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