Time course of antipsychotic effects of neuroleptic drugs
Abstract
The authors reviewed relevant studies in an attempt to define the onset and time course of antipsychotic effects of neuroleptic drugs. After excluding open trials, studies of chronically psychotic patients, and studies not using a placebo or nonneuroleptic sedative as a control, they found only five reports suitable for analysis. Among these, the degree of patients' improvement during neuroleptic treatment was similar regardless of the duration of the study. Also, in studies comparing neuroleptics with sedatives, similar improvement was observed with both treatments. Although neuroleptic drugs have been used clinically for 35 years, the timing of their specific therapeutic effects remains unclear.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).
