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Abnormal prolactin response to haloperidol challenge in men with schizophrenia

Published Online:https://doi.org/10.1176/ajp.144.10.1335

Fourteen drug-free male patients with schizophrenia had a smaller and slower prolactin response to 0.5 mg of intravenous haloperidol than 14 normal age- and sex-matched control subjects. This finding supports the presence of dopaminergic dysfunction in schizophrenia.

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