Factors Associated with Poor Response to Lithium Carbonate: A Clinical Study
Abstract
Eighteen patients with intermittent manic illness were treated with lithium on a regular basis for an average of two years. An attempt was made to characterize factors related to suboptimal treatment response. A "crisis" state in reaction to a stressful event was observed in suboptimal responders at the time of lithium failure, and a concurrent rise in urinary 17-hydroxycorticosteroid excretion was noted. Possible relationships among lithium ion, metabolic factors, and altered clinical state are discussed.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).