Critique of Studies of Lithium Salts in the Treatment of Mania
Abstract
The authors review all available studies of lithium therapy of mania (comprising 805 patients) to determine whether lithium's pharmacologic efficacy has been demonstrated in the customary manner. All studies reviewed except for one were found to have serious methodological deficiencies. The authors conclude that the available data demonstrate neither efficacy nor inefficacy, primarily because of inadequate experimental design.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).
