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Published Online:https://doi.org/10.1176/ajp.124.8.1063

Psychiatric observations of mood, thought content, and social behavior of 12 volunteer subjects prior to, during, and following an experimental drinking situation were carried out. Contrary to commonly-held impressions concerning alcoholics, most of the subjects experienced an increase rather than a decrease in anxiety and depression; no subject reported subjective craving for alcohol following his first drink; the subjects maintained a high degree of social interaction with other patients and disruptive behavior was rare.

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