TREATMENT OF PSYCHIATRIC PATIENTS WITH A PHENOTHIAZINE DERIVATIVE (PROCHLORPERAZINE) WITH SPECIAL REFERENCE TO AFTER CARE
Abstract
1. Prochlorperazine has proved to be an effective drug for the treatment of acute psychotic conditions and for maintenance therapy in an after care setting of chronic psychiatric patients. It is particularly valuable in paranoid states and schizophrenia. Frequent side effects (53%) especially of the extrapyramidal type were generally controlled without difficulty by the addition of anti-parkinsonian drugs.
2. Frequently, discontinuation or decrease of the dose of prochlorperazine resulted in exacerbation of symptoms, which in most cases responded promptly to resumption of maintenance therapy or to increase of dosage.
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