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Published Online:https://doi.org/10.1176/ajp.116.3.222

A series of 18 consecutive patients were selected for frontal lobe surgery over a 10 year period to obtain relief from chronic, intractable anxiety. Of the 13 who were not psychotic, 12 have returned to a well adjusted, independent existence at home without further hospitalization or continuation of therapy. Certain observations based on these case studies have been made, with full realization that generalizations cannot be drawn from 18 cases and that whatever value this study may have is dependent upon intense personal investigation of all relevant factors in a small group of individuals.

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