FATALITIES IN PATIENTS RECEIVING CHLORPROMAZINE AND RESERPINE DURING 1956-1957 AT PILGRIM STATE HOSPITAL
Abstract
1. Fatalities in the course of treatment with chlorpromazine and reserpine are much lower than with other somatic therapies.
2. Cardio-vascular and respiratory fatalities seen as the main complication with other somatic therapies are not as important complications in the course of treatment with these 2 drugs.
3. In patients with brain damage, asphyxia as the cause of death is due rather to a "masked fit" or "unnoticed convulsion" than to lack of cough reflex or some specific respiratory effect.
4. The development and appearance of ruptered peptic ulcer or a "silent" ulcer in patients receiving ataraxics should be further investigated.
5. The disappearance of the classical syndrome of "psychotic exhaustion" as a cause of death in the years of the use of ataraxics is remarkable and must be reemphasized.
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