Antipsychotic effect of buprenorphine in schizophrenia



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	Articles by Emrich, H. M.

Am J Psychiatry 1987; 144:1340-1342
Copyright © 1987 by American Psychiatric Association

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Antipsychotic effect of buprenorphine in schizophrenia

C Schmauss, A Yassouridis and HM Emrich
Max Planck Institute for Psychiatry, Munich.

The antipsychotic potency of the partial opiate agonist buprenorphine was evaluated in 10 neuroleptic-free schizophrenic patients suffering from frequent hallucinations, delusions, and severe formal thought disorders. Buprenorphine had a pronounced antipsychotic effect, which lasted about 4 hours, in patients with schizophreniform disorders (N = 4) and paranoid schizophrenia (N = 3).

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