Am J Psychiatry 1986; 143:1587-1590
Copyright © 1986 by American Psychiatric Association
Symptoms of neuroleptic malignant syndrome in 82 consecutive inpatients
G Addonizio, VL Susman and SD Roth
This study, a retrospective chart review of 82 consecutive male inpatients,
assessed the spectrum and prevalence of neuroleptic malignant syndrome. The
prevalence of diagnosed neuroleptic malignant syndrome (2.4%) was greater
than that generally reported. Eight additional patients manifested symptoms
that abated without cessation of neuroleptic treatment. This suggests that
neuroleptic malignant syndrome is a spectrum disorder that has milder
variants. Affective illness may be a risk factor for its development.
